型号：GM-J#030061 -Cryorecovery

应用：Tbx18-Cre mice have an iCre recombinase sequence with expression being driven by the the T-box18 promoter on a BAC transgene. These mice express iCre in the lower urinary tract.

型号：GM-J#030047 -Cryorecovery

应用：Nkx2.5-Cre knock-in/knock-out allele was designed to both abolish endogenous gene function and allow the Nkx2-5 promoter/enhancer regions to direct Cre recombinase expression to embryonic heart, as well as developing tongue, thymus and spleen. These mice may be useful for recombining lox-flanked (floxed) alleles in studying cardiac development.

型号：GM-J#030005 -Not Available At Jax

应用：This strain has been discontinued. Please search the JAX Mice database for other strains which may be suitable for your studies, or contact Technical Support for assistance.

型号：GM-J#029926 -Cryorecovery

应用：NG2-cre transgenic mice express Cre recombinase in Cspg4 expressing pericytes. These mice may be useful for Cre-lox studies related to the role of Cspg4 expressing pericytes in cancer progression and fibrosis.

型号：GM-J#029925 -Cryorecovery

应用：These aSMA-cre transgenic mice express Cre recombinase in Acta2 expressing myofibroblasts. These mice may be useful for Cre-lox studies related to the role of aSMA+ fibroblasts in cancer progression and fibrosis.

型号：GM-J#029899 -Available

应用：The NuTRAP allele (Nuclear tagging and Translating Ribosome Affinity Purification) has a loxP-flanked STOP preventing transcription of three individual components: BirA, BLRP-tagged mCherry/mRANGAP1 and EGFP/L10a. When expressed, the BLRP-tagged mCherry/mRANGAP1 protein is biotinylated by BirA, allowing nuclear membrane-labeling with mCherry and biotin (which enables nuclear isolation by fluorescence- and affinity-based purification). Furthermore, EGFP/L10a fluorescently tags the translating mRNA polysome complex (which enables isolation of RNAs that are actively engaged by ribosomes). Overall, NuTRAP mice are a Cre-inducible tool strain that allows labeling and simultaneous isolation of cell type-specific nuclei and mRNA, and are well-suited for studying epigenomics and transcriptomics from specific cell types within a heterogeneous tissue. Of note, the donating investigator also has available their similar mouse line H2B-TRAP (Stock No. 029789).

型号：GM-J#029893 -Cryorecovery

应用：Cre-mediated excision of a floxed Stop cassette enables directed expression of the human tetherin (BST2) cDNA and an EGFP reporter useful in studies of viral infection.

型号：GM-J#029855 -Cryorecovery

应用：These Snca floxΔneo ROSA26-stop-lacZ reporter mice carry a floxed allele of the Snca gene and the Gt(ROSA)26Sortm1Sho Cre reporter allele. This strain may be useful for generating mutants in which Cre recombinase efficiency can be monitored for applications related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.

型号：GM-J#029847 -Cryorecovery

应用：These Ret-EGFP knock-in/knock-out mice express the EGFP reporter under the control of the endogenous promoter and are useful in studies of neural and renal development.

型号：GM-J#029803 -Cryorecovery

应用：This Ki67cre/ERT2 knock-in strain expresses tamoxifen inducible Cre recombinase in actively dividing cells.