型号：GM-J#030384 -Cryorecovery

应用：These transgenic BAC mice express tamoxifen-inducible cre-ERT2 from the mouse Htr6 promoter. Expression occurs in Htr6-expressing cells, including a subclass of excitatory interneurons in the dorsal horn of the spinal cord.

型号：GM-J#030383 -Cryorecovery

应用：These transgenic BAC mice express tamoxifen-inducible cre-ERT2 from the mouse Cdh3 promoter. Expression occurs in Cdh3-expressing cells, including a subclass of inhibitory interneurons in the dorsal horn of the spinal cord.

型号：GM-J#030379 -Cryorecovery

应用：These transgenic BAC mice express cre recombinase from the mouse Abcb1a promoter. When crossed with mice carrying loxP-flanked sequences of interest, the floxed region is excised in endothelial cells.

型号：GM-J#030357 -Cryorecovery

应用：This knock-in/knock-out strain expresses cre recombinase from the Pou4f2 promoter. Homozygosity results in a reduction in retinal ganglion cells (RGCs). Cre expression is observed in the retina, brain, intestines, heart, and gonads. Males carrying both this Pou4f2Cre allele and a floxed region of interest produce progeny that exhibit a widespread pattern of germline expression in all tissues tested.

型号：GM-J#030332 -Cryorecovery

应用：The CyclinA2-lacZ-EGFP BAC transgenic mouse line (or CyclinA2-floxed:LacZ-GFP) is a robust and sensitive reporter of cell cycle activity in any cell type of interest - enabling the visualization of cell cycle activity in specific cell types. These CyclinA2-fusion reporter mice are designed to express CyclinA2-lacZ (CyclinA2-βgal) prior to Cre recominase exposure, and CyclinA2-EGFP following Cre recombination.

型号：GM-J#030329 -Cryorecovery

应用：D1-Cre YAC transgenic mice have Cre recombinase expressed from the mouse Drd1a promoter. The spatio-temporal pattern of Cre expression in dopaminoceptive neurons is reported to closely recapitulate that of the endogenous Drd1a gene in embryonic and adult stages.

型号：GM-J#030328 -Available

应用：Ai148(TIT2L-GC6f-ICL-tTA2)-D (also called Ai148D) mice are a Cre-dependent, Tet-controllable, fluorescent calcium-indicator tool strain, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Exposure to Cre recombinase removes both STOP cassettes, resulting in expression of tTA2 and GCaMP6f (a bright EGFP fluorescent calcium indicator of single neuronal action potentials with fast response kinetics). GCaMP6f expression may then be diminished/eliminated by doxycycline.

型号：GM-J#030323 -Available Now

应用：Fos2A-iCreER knock-in (also called Fos2A-iCreERT2 or "TRAP2") was designed to have expression of a tamoxifen-inducible, improved Cre recombinase (icre/ERT2) from the Fos promoter/enhancer elements - without disrupting endogenous Fos expression. Fos2A-iCreER mice are a Cre-lox tool allowing inducible iCre recombination in Fos-expressing cells/tissues (including neurons activated by specific somatosensory, visual and auditory stimuli) or behavioral experiences such as enriched environment, fear conditioning or water deprivation. Immediate early genes (IEGs) are the connection between gene expression and a neuron's electrical/synaptic activity (which defines neuronal response properties).

型号：GM-J#030305 -Cryorecovery

应用：Cre-mediated excision of a floxed STOP enables tissue-specific expression of EGFP-tagged ribosomal protein that enables transcriptional profiling using TRAP technology. Expression of EGFP/RPL10a is driven by Eef1a1, a strong promoter that is widely expressed at high levels in the nervous system and in most tissues.

型号：GM-J#030291 -Cryorecovery

应用：These targeted knock-in/knock-out mutant mice express tamoxifen-inducible cre-ERT2 fusion protein from the mouse Ntrk3/TrkC promoter. Expression occurs in Ntrk3-expressing cells, including subsets of dorsal root ganglia neurons and the spinal cord.