型号：GM-J#029582 -Cryorecovery

应用：This CRISPR/Cas9 generated mutant of the Trpv4 gene carries a cre/ERT2 knock-in mutation.

型号：GM-J#029575 -Cryorecovery

应用：These Hmga2CK mice possess pairs of variant loxP sites on either side of exon 2 and a SA-GFP-SD cassette (in reverse orientation) in intron 2 of the Hmga2 gene. Cre-recombination puts GFP under the control of all of the endogenous regulatory elements of endogenous Hmga2 (while also creating a null allele). Applications may include growth, development, transcriptional regulation and cancer metastasis.

型号：GM-J#029567 -Available

应用：This Col1a2 Cre-ER mutant mouse strain carries a transgene with tamoxifen inducible Cre recombinase and may be useful for generating fibroblast specific targeted mutants for studies of fibrotic diseases, wound healing and connective tissue physiology, as well as fibroblast lineage fate mapping.

型号：GM-J#029566 -Cryorecovery

应用：These Isl1 MerCreMer knock-in mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the Isl1 gene. When induced, cre activity is observed in Isl1 expressing cells in embryos. These mice may be useful for generating conditional mutations for studying cell lineages during development of the nervous system, heart, pituitary gland, pancreas and stomach.

型号：GM-J#029498 -Cryorecovery

应用：This CRISPR/Cas9 generated mutant of the Gfra3 gene carries a cre/ERT2 knock-in mutation.

型号：GM-J#029490 -Cryorecovery

应用：The doxycycline-regulated Nkx2.5 enhancer-eGFP/Cre transgenic mice have the cardiac-specific mouse NK2 homeobox 5 promoter/enhancer sequences directing dox-controllable expression of eGFP/Cre fusion protein to early heart progenitor cells (cardiomyoblasts) from embryonic day (E)7.5-E11.5. These Nkx2.5 enh-GFP-Cre transgenic mice allow Nkx2.5+ cardiomyoblast fluorescent labeling (cell isolation by FACS) and lineage tracing in a doxycycline-regulated fashion.

型号：GM-J#029486 -Cryorecovery

应用：The RC::FrePe dual-recombinase responsive fluorescent allele has a frt-flanked STOP and loxP-flanked mCherry::STOP all preventing transcription of eGFP. FLP recombinase results in mCherry fluorescence, and further exposure to Cre recombinase results in eGFP fluorescence in the overlapping populations. The RC::FrePe allele and its derivatives are useful for fluorescent labeling of cells/tissues in embryonic or adult mice. These mice allow intersectional genetic fate mapping of different cell subpopulations defined by the overlap of two gene expression domains.

型号：GM-J#029485 -Cryorecovery

应用：These Gsx1cre transgenic mice express Cre recombinase under the control of the Gsx1 promoter and may be useful for generating conditional mutations for studying gain/loss of function or fate mapping in Gsx1 expressing neurons.

型号：GM-J#029481 -Not Available At Jax

应用：This strain is extinct. Please search the JAX® Mice Database for similar inducible tissue-specific cre strains.

型号：GM-J#029428 -Cryorecovery

应用：The Cdh6CreER (Cdh6-CreER) knock-in/knock-out allele was designed to both abolish endogenous gene function and allow the Cdh6 promoter/enhancer regions to direct tamoxifen-inducible Cre recombinase expression to ON-OFF direction-selective retinal ganglion cells (ooDSGCs) that respond to vertical motion (dorsal and ventral), as well as to starburst amacrine cells. These mice may be useful for tamoxifen-inducible recombination of lox-flanked (floxed) alleles in studying photoreceptors and retinal circuitry.