型号：GM-J#007742 -Available

应用：These smMHC(Myh11)/Cre/eGFP transgenic mice may be useful in studies utilizing "Cre-lox" technology or fluorescent protein expression in smooth muscle, especially separation of vascular myocytes from the surrounding cellular environment to isolate muscle specific adaptations or disease responses.

型号：GM-J#007684 -Cryorecovery

应用：These knock-in mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the atonal homolog 1 (Drosophila) (Atoh1, also referred to as Math1) gene. When induced, cre activity is observed in neural progenitors of the cerebellar rhombic lip, dorsal hindbrain and spinal cord, as well as in inner-ear primordial. These mice may be useful in studying cerebellum development and fate mapping of Math1/Atoh1 cells.

型号：GM-J#007677 -Available

应用：GAD67-GFP (line G42) mice may be useful for fluorescent labeling of the Pv-expressing subset of GABAergic neurons, allowing reliable and efficient characterization of perisomatic innervation in vitro.

型号：GM-J#007676 -Available Now

应用：mT/mG (also called ROSAmT/mG) is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Prior to Cre recombination, cell membrane-localized tdTomato (mT) fluorescence expression is widespread in cells/tissues. Cre recombinase expressing cells (and future cell lineages derived from these cells) have cell membrane-localized EGFP (mG) fluorescence expression replacing the red fluorescence.

型号：GM-J#007673 -Cryorecovery

应用：These GAD67-GFP (line 3) mice may be useful for fluorescent labeling of neurons and studying the development, maturation, regulation, and functional integration of newborn neurons in adult hippocampus.

型号：GM-J#007610 -Cryorecovery

应用：These transgenic mice (“SLICK” for single-neuron labeling with inducible Cre-mediated knock-out) have a tamoxifen inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest, the offspring are useful for generating tamoxifen-induced, Cre-mediated targeted neuron-specific deletions only in neurons that express Yellow Fluorescent Protein. The Donating Investigator reports that founder line V mice express the transgene sparsely in neurons of the central nervous system.

型号：GM-J#007606 -Cryorecovery

应用：These transgenic mice ("SLICK" for single-neuron labeling with inducible Cre-mediated knock-out) have a tamoxifen inducible Cre-mediated recombination system and Enhanced Yellow Fluorescent Protein driven by 2 bidirectional copies of the mouse thymus cell antigen 1 promoter. When crossed with a strain containing a loxP site flanked sequence of interest. The Donating Investigator reports that founder line A mice express the transgene in small subsets of motor neurons and dorsal root ganglion neurons.

型号：GM-J#007587 -Cryorecovery

应用：Mice carrying this mutation are viable, fertile, and display no apparent defects or abnormalities. Mutations in the human homolog of this gene are associated with autosomal juvenile parkinsonism, a heritable form of Parkinson's disease.

型号：GM-J#007576 -Cryorecovery

应用：mT/mG (also called ROSAmT/mG) is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Prior to Cre recombination, cell membrane-localized tdTomato (mT) fluorescence expression is widespread in cells/tissues. Cre recombinase expressing cells (and future cell lineages derived from these cells) have cell membrane-localized EGFP (mG) fluorescence expression replacing the red fluorescence.

型号：GM-J#007567 -Cryorecovery

应用：These CD11c-Cre-GFP transgenic mice may be useful in immunological studies utilizing Cre-lox technology or fluorescent protein expression in dendritic cells.