型号：GM-J#006823 -Available

应用：These Hualpha-Syn(A53T) transgenic mice display an age-dependent phenotype including progressive motor deficits, intraneuronal inclusion bodies and neuronal loss. This line may be useful for studying Parkinson's disease and other synucleinopathies associated with motor neuron loss and ubiquitinated inclusions in the brain stem and the spinal cord, Lewy bodies, and synaptic plasticity.

型号：GM-J#006785 -Available

应用：The CD19-Cre knock-in/knock-out allele has a Cre recombinase gene inserted into the first coding exon of the CD19 antigen gene; both abolishing endogenous Cd19 gene function and placing cre expression under the control of the endogenous Cd19 promoter/enhancer elements. Cre recombinase expression is directed at the earliest stages and throughout B-lymphocyte development and differentiation. Homozygous mice are also useful for studying B cell-deficiency.

型号：GM-J#006774 -Cryorecovery

应用：When these Col2CreERT mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in cartilage cells (both during embryogenesis and postnatally), as well as in other cell types that normally express the endogenous Type II collagen gene.

型号：GM-J#006721 -Cryorecovery

应用：This strain expresses a nuclear localized Cre recombinase in the subset of olfactory sensory neurons that would normally express Or2b4 (formerly Olfr124).

型号：GM-J#006677 -Cryorecovery

应用：These Cre recombinase mice are useful in studies to identify olfactory sensory neuronal development and topography in glomeruli in the olfactory bulb.

型号：GM-J#006668 -Cryorecovery

应用：These Cre recombinase mice are useful in studies to identify olfactory sensory neuronal lineage and topography in glomeruli in the olfactory bulb.

型号：GM-J#006663 -Cryorecovery

应用：The expression of Cre in these mice is driven by the promoter region of the rat neuron specific enolase (NSE or Eno2) gene and directed to neurons with expression in many tissue types.

型号：GM-J#006660 -Available Now

应用：DATIREScre knock-in mice have Cre recombinase expression directed to dopaminergic neurons, without disrupting endogenous dopamine transporter expression. These mice may be useful for studying gene function in dopaminergic neurons, such as drug addiction, Parkinson's disease and Attention Deficit-Hyperactivity Disorder (ADHD).

型号：GM-J#006618 -Cryorecovery

应用：Under the control of a tetracycline-responsive promoter element (tetO) these mice express yellow fluorescent protein (EYFP) specifically in neuronal mitochondria.

型号：GM-J#006600 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.