型号：GM-J#007921 -Cryorecovery

应用：These Brainbow 2.1 (founder line R) mice allow labeling of individual neurons in peripheral and central neurons with nuclear localized, membrane-targeted, or cytoplasmic fluorescent proteins in cre recombined cells, and may also be useful in conjunction with other Brainbow strains (Stock No. 007901, Stock No. 007910, Stock No. 007911) for neurobiological studies.

型号：GM-J#007920 -Cryorecovery

应用：These Ai2 mice harbor a targeted mutation of the Gt(ROSA)26Sor locus with a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven enhanced yellow fluorescent protein (EYFP), and may be useful as a Cre reporter strain. EYFP is expressed following Cre-mediated recombination.

型号：GM-J#007917 -Cryorecovery

应用：En1-CreERT1 mutant mice harbor the Cre-ERT1 fusion gene under control of the endogenous engrailed 1 locus. When En1-CreERT1 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in En1-expressing tissues (including the mesencephalon and rhombomere 1, as well as the developing cerebellum, dermis, and limbs).

型号：GM-J#007916 -Cryorecovery

应用：These En1Cki (or En1Cre) mutant mice harbor a Cre recombinase (cre) "knock-in" allele that also abolishes endogenous gene function and may be useful for Cre-lox applications studying engrailed protein function such as deleting genes in spinal cord V1 interneurons, the embryonic mesencephalon and rhombomere 1 by E9, as well as in the ventral ectoderm of the limbs, in a subset of somite cells, and some mesoderm-derived tissues.

型号：GM-J#007915 -Cryorecovery

应用：These Amh-cre transgenic mice have expression of Cre recombinase directed by the testis Sertoli cell-specific promoter elements of the anti-Mullerian hormone (Amh) gene. These Amh-cre transgenic mice may be useful in generating conditional knockouts in testis Sertoli cells for studying male embryonic sexual differentiation and the regulation of spermatogenesis.

型号：GM-J#007914 -Available Now

应用：Ai14 is a Cre reporter tool strain designed to have a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. Ai14 mice express robust tdTomato fluorescence following Cre-mediated recombination. This strain is congenic on the C57BL/6J genetic background.

型号：GM-J#007913 -Available

应用：When these Gli1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Gli1 expressing cells; making them useful for studying axis patterning, proliferation, and cell fate specification of Hedgehog responding cells at different stages of embryogenesis.

型号：GM-J#007912 -Cryorecovery

应用：These En-1lki (or En1lacZ) mutant mice harbor a β-galactosidase "knock-in" allele that abolishes endogenous gene function and may be useful for reporter protein expression in En1-expressing tissues in studying engrailed protein function in limb patterning along the dorso-ventral axis, spinal cord V1 interneuron development, embryonic mesencephalon and rhombomere 1 (cerebellum) development, as well as developing somites, and skin.

型号：GM-J#007911 -Cryorecovery

应用：These Brainbow 1.1 (founder line M) mice allow mutually exclusive expression of three membrane-targeted fluorescent proteins in astrocytes (including glia) throughout the brain, providing unambiguous delineation of boundaries between adjacent astrocytes in cre recombined cells, and may also be useful in conjunction with other Brainbow strains (Stock No's. 007901, 007910, and 007921) for neurobiological studies.

型号：GM-J#007910 -Cryorecovery

应用：These Brainbow transgenic mice allow labeling of individual neuronal types with approximately 166 distinguishable color variations in cre recombined cells, and may also be useful in conjunction with other Brainbow strains for neurobiological studies.