型号：GM-J#035573 -Cryorecovery

应用：Avpr1a1iCre:GFP knock-in mice should express iCre:GFP wherever Avpr1a (arginine vasopressin receptor 1A), a G protein-coupled receptor (GPCR), is normally expressed. Expression levels of the targeted gene have not been assessed, but no effect is anticipated as the insertion is beyond the termination codon.

型号：GM-J#035572 -Cryorecovery

应用：Adcyap1r1iCre:GFP knock-in mice should express iCre:GFP wherever Adcyap1r1 (adenylate cyclase activating polypeptide 1 receptor 1), a G protein-coupled receptor (GPCR), is normally expressed. Expression levels of the targeted gene have not been assessed, but no effect is anticipated as the insertion is beyond the termination codon.

型号：GM-J#035554 -Cryorecovery

应用：Lfng-CreERT2 transgenic mice have a cre/ERT2 fusion gene under direction of the mouse LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Lfng, also known as Lunatic fringe) promoter/enhancer sequences. These mice retain normal endogenous Lfng expression and have tamoxifen-inducible Cre expressed in neural stem cells of the hippocampus.

型号：GM-J#035552 -Cryorecovery

应用：Tecta-Cre knock-in/knock-out mice express Cre recombinase under direction of the tectorin alpha (Tecta) promoter in the sensory epithelium in the cochlea. Homozygous mice are deaf, while heterozygous mice are not. These mice are useful when studying congenital deafness.

型号：GM-J#035549 -Cryorecovery

应用：Color-Switch PER2::LUC reporter mice switch from click beetle red PER2 (period circadian clock 2)::LUCIFERASE protein expression to click beetle green PER2::LUCIFERASE expression upon cre recombination. This enables cell-type-specific circadian measurements.

型号：GM-J#035547 -Cryorecovery

应用：Mmp3 null mice carry a CRISPR/Cas9 generated 1 bp deletion in the catalytic domain of the matrix metallopeptidase 3 (Mmp3), resulting in a premature stop codon, making this strain useful when studying protective responses at the level of the neurovascular unit upon central nervous system injury.

型号：GM-J#035452 -Cryorecovery

应用：Uts2bCre (Uts2b2A-Cre) mice express a CRISPR/Cas9-generated T2A-cre recombinase knock-in from the mouse Uts2b (urotensin 2B) promoter. Reporters indicate that cre expression patterns are identical to those of the endogenous Uts2b gene based on in situ hybridization (ISH) results available through the Allen Brain Institute. This strain has been useful in the mapping of vagal sensory neurons in the intestine.

型号：GM-J#035435 -Available

应用：Xcr1Cre knock-in mice express an mCherry fluorescent protein and an icre recombinase sequence under the direction of the Xcr1 promoter in conventional type 1 dendritic cells (cDC1).

型号：GM-J#035412 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#035404 -Cryorecovery

应用：TIGRE-MORF(Ai166) is one of a set of a Cre reporter tool strains (also including MORF1 and MORF3) that use mononucleotide repeat frameshift (MORF) as a translation switch for cell labeling in vivo. TIGER-MORF (Ai166) mice express a cre-dependent tetracycline-activated EGFP fluorescent protein that is proceeded by a polyguanine repeat (G22) MORF switch. Exposure to Cre recombinase removes both STOP cassettes unblocking EGFP fluorescence and tTA2 expression and in the presence of spontaneous frameshift the EGFP reporter provides sparse and stochastic labeling of neural cells. In addition, reporter expression may be diminished/eliminated by doxycycline. TIGER-MORF(Ai166) can be used for high level direct fluorescent sparse labeling of Cre+ neuronal and glial cells.