型号：GM-J#035925 -Cryorecovery

应用：Opn4Cre knock-in/knock-out mice express Cre recombinase under the direction of the Opn4 promoter in melanopsin-expressing retinal ganglion cells and amacrine cell layers of the retina.

型号：GM-J#035901 -Cryorecovery

应用：Kcnma1fl-tdTomato conditional mutant mice possess loxP sites flanking exon 2 and a tdTomato reporter (that only expresses upon cre recombination) in the Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) gene and may be useful in generating conditional mutations to study the function of BK currents.

型号：GM-J#035878 -Cryorecovery

应用：MvhCre-mOrange (Ddx4-Cre) knock-in/knock-out mice express Cre recombinase from the mouse Ddx4 (DEAD box helicase 4; also called Mvh) promoter. An mOrange fluorescent reporter in the construct does not appear to be functional. Expression of Ddx4 is blocked. Cre recombinase activity is found in the gonads as early as embryonic day 1.5. Whole embryo recombination has been observed.

型号：GM-J#035877 -Cryorecovery

应用：MvhCre-mOrange (Ddx4-Cre) knock-in/knock-out mice express Cre recombinase from the mouse Ddx4 (DEAD box helicase 4; also called Mvh) locus. An mOrange fluorescent reporter in the construct does not appear to be functional. Expression of Ddx4 is blocked. Cre recombinase activity is found in the gonads as early as embryonic day 14.5. Variable whole embryo recombination has been observed.

型号：GM-J#035789 -Cryorecovery

应用：CAG-Stop-Dmrt1-Gfp knock-in mice conditionally express Dmrt1 (doublesex and mab-3 related transcription factor 1) and an EGFP reporter. This strain may be useful for studying vertebrate sex determination.

型号：GM-J#035764 -Available

应用：Jchain-CreERT2 knock-in mice have the endogenous immunoglobulin joining chain promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase, and are on a congenic C57BL/6N background. These mice are a Cre-lox tool allowing inducible Cre recombination with high specificity for B cells, and may be useful in studying immunology and infectious disease.

型号：GM-J#035717 -Available

应用：Il17aCre knock-in/knock-out mice express a codon improved Cre recombinase knocked into the endogenous Il17a gene. This targeted mutation abolishes Il17a expression. These mice may be useful for fate mapping IL17A secretion during T helper cell activation.

型号：GM-J#035703 -Cryorecovery

应用：Igfbp2-CreERT2 knock-in mice have the endogenous insulin-like growth factor binding protein 2 promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase. These mice are a Cre-lox tool allowing inducible Cre recombination in Igfbp2-expressing cells/tissues (including pulmonary AT1 cells), and may be useful in studying developmental biology and lung cell differentiation and regeneration.

型号：GM-J#035702 -Cryorecovery

应用：ErGFPcre knock-in/knock-out mice have an EGFP reporter fused to an iCre recombinase cDNA inserted into the 5’ UTR of the erythropoietin receptor (Epor) gene. EGFP/iCre is expressed by erythroid progenitors. This strain may be useful as a reporter for lineage tracing and a Cre-lox tool for deletion of floxed sequences in cells in the erythroid lineage.

型号：GM-J#035699 -Cryorecovery

应用：LoxP-STOP-loxP-SAA3 (also called LSL-SAA3) knock-in mice carry a conditional mutant allele in which Saa3 (serum amyloid A 3) and IRES-EGFP are over-expressed from a CAG promoter upon Cre recombinase-mediated excision of a loxP-flanked neomycin/Stop cassette. EGFP expression has not been assessed. This strain has been useful in studies of Th17 cell responses, inflammation, and autoimmunity.