型号：GM-J#034799-JAX -Cryorecovery

应用：These microRNA let7d conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is observed in embryonic brain and spinal cord. This mutant mouse strain may be useful in studies of microRNA biology.

型号：GM-J#034798-JAX -Cryorecovery

应用：These microRNA 7b conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. LacZ expression is observed in embryonic brain and spinal cord. This mutant mouse strain may be useful in studies of microRNA biology.

型号：GM-J#034796 -Cryorecovery

应用：Foxn1ex9cre mice express Cre recombinase from the endogenous Foxn1 (forkhead box N1) locus without disruption of the Foxn1 coding sequence. When crossed with a strain containing loxP site-flanked sequence, Cre-mediated recombination results in deletion of the flanked region in thymic epithelial cells and keratinocytes.

型号：GM-J#034795 -Cryorecovery

应用：When these CAGGCre-ERTM mice are bred with mice carrying a floxed target gene, tamoxifen-inducible Cre-mediated recombination results in deletion of the floxed sequences in widespread cells or tissues of the offspring, including developing embryos and cultured cells derived from transgenic mice.

型号：GM-J#034749 -Cryorecovery

应用：ROSA26DR-SV-HRP mice conditionally express synaptic vesicle (SV)-targeted horseradish peroxidase (HRP) in a Cre and Flp dual recombinase (DR)-dependent manner. Concurrent Cre and Flp recombinase-mediated excision of loxP- and FRT-flanked Stop cassettes enables directed expression of horseradish peroxidase fused to a synaptic vesicle retention signal, useful in multiplexed electron microscopy labeling.

型号：GM-J#034748 -Cryorecovery

应用：ROSA26DR-ER-HRP mice conditionally express endoplasmic reticulum (ER)-targeted horseradish peroxidase (HRP) in a Cre and Flp dual recombinase (DR)-dependent manner. Concurrent Cre and Flp recombinase-mediated excision of loxP- and FRT-flanked Stop cassettes enables directed expression of horseradish peroxidase fused to an endoplasmic reticulum retention signal, useful in multiplexed electron microscopy labeling.

型号：GM-J#034747 -Cryorecovery

应用：ROSA26LSL-SV-HRP mice conditionally express synaptic vesicle (SV)-targeted horse radish peroxidase (HRP) in a Cre recombinase-dependent manner. Cre recombinase-mediated excision of a loxP-flanked Stop cassette enables directed expression of horse radish peroxidase fused to a synaptic vesicle retention signal, useful in multiplexed electron microscopy labeling.

型号：GM-J#034746 -Cryorecovery

应用：ROSA26LSL-ER-HRP mice conditionally express endoplasmic reticulum (ER)-targeted horse radish peroxidase (HRP) in a Cre recombinase-dependent manner. Cre recombinase-mediated excision of a loxP-flanked Stop cassette enables directed expression of horse radish peroxidase fused to an endoplasmic reticulum retention signal, useful in multiplexed electron microscopy labeling.

型号：GM-J#034736 -Cryorecovery

应用：vGlut3-P2A-iCreERT2 mice carry a CRISPR/Cas9 generated insertion of a P2A-iCre/ERT2 cassette in exon 12, immediately before the stop codon of the Slc17a8 gene, without disrupting endogenous vesicular glutamate transporter 3 expression. These mice may be used to generate tamoxifen-induced conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic synaptic vesicle trafficking.

型号：GM-J#034727 -Available

应用：P2ry12-CreER mice express a tamoxifen-inducible Cre driven by the endogenous purinergic receptor P2Y, G-protein coupled 12 (P2ry12) promoter. These mice are a Cre-lox tool, allowing inducible Cre recombination in P2ry12-expressing cells/tissues (primarily microglia), and may be useful in studying neuroinflammation, neurodegenerative disease, and immune response.