型号:GM-J#036062-JAX -Cryorecovery
应用:These microRNA 9-2 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#036061-JAX -Cryorecovery
应用:These microRNA 10b conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#036061 -Cryorecovery
应用:These loxP-BphP1 mice are a Cre-dependent, Tet-controllable optogenetic line, created by targeted insertion of a CAG promoter, loxP-flanked EGFP-polyA cassette and the photoreceptor/fluorescent/tet-repressor fusion protein (RpBphP1/mCherry/TetR) into the the Gt(ROSA)26Sor locus. Widespread EGFP expression is replaced by RpBphP1/mCherry/TetR fusion protein expression upon Cre recombinase exposure. Further introduction of a BphP1 binding partner::nuclear-localization tag::VP16 activation domain construct and a tetO (TRE) promoter-driven reporter gene allow the subsequent control of reporter gene expression via illumination with near-infrared (NIR) light (~740-780 nm) as well as tetracycline/doxycycline.
型号:GM-J#036060-JAX -Cryorecovery
应用:These microRNA 21 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#036059-JAX -Cryorecovery
应用:These microRNA cluster 29 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#036058-JAX -Cryorecovery
应用:These microRNA 138-1 conditional mutant mice are designed to generate a null allele or a lacZ tagged null allele when combined with Flp or Cre recombinase expressing strains. This mutant mouse strain may be useful in studies of microRNA biology.
型号:GM-J#036054 -Cryorecovery
应用:Lbhd2-CreERT2 knock-in mice have the endogenous LBH domain containing 2 promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase. These mice are a Cre-lox tool allowing inducible Cre recombination in Lbhd2-expressing cells/tissues (including mitral cells of the olfactory bulb), and may be useful in studying neural development and olfactory neurocircuitry.
型号:GM-J#035978 -Cryorecovery
应用:Hoxb8-ICre knock-in mice express Cre recombinase from the mouse Hoxb8 (homeobox B8) promoter. Expression of Hoxb8 is not disrupted in this knock-in line. When used in combination with conditional reporter strains (e.g. Gt(ROSA)26Sortm1(EYFP)Cos Stock No. 006148), this strain allows you to visualize a subset of microglia for modulating anxiety.
型号:GM-J#035973 -Cryorecovery
应用:Rpe65CreERT2 knock-in mice have a P2A-CreERT2 coding region fused in-frame after the last amino acid-encoding codon of the endogenous retinal pigment epithelium 65 (Rpe65) gene. They are useful for studying gene function and pathophysiology of retinal diseases in the retinal pigment epithelium.
型号:GM-J#035926 -Cryorecovery
应用:Opn4CreERT2 knock-in/knock-out mice express cre/ERT2 under the direction of the Opn4 promoter. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in melanopsin-expressing retinal ganglion cells and amacrine cell layers of the retina.