型号：GM-J#038640 -Available For Pre-Order

应用：CRISPR/Cas9 generated Rtkn2CreER knock-in/knock-out mice have cre-ERT2 replacing the start codon of the endogenous rhotekin 2 gene. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in lung alveolar type 1 cells.

型号：GM-J#038639 -Available For Pre-Order

应用：ROSAKaleidoscope mice carry three fluorescent cell biology reporters separated by 2A self-cleaving sequences downstream of a floxed STOP cassette inserted into the ubiquitous Gt(ROSA)26Sor gene. These mice are a tricolor tunable reporter mouse line useful for simultaneous imaging of lysosomes, mitochondria, and microtubules in the native tissues at a single-cell resolution.

型号：GM-J#038602 -Available For Pre-Order

应用：CRISPR/Cas9 generated Car4CreER knock-in/knock-out mice have cre-ERT2 replacing the start codon of the endogenous carbonic anhydrase 4 gene. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in Cap2 pulmonary endothelial cells called aerocytes.

型号：GM-J#038595 -Cryorecovery

应用：X-linked DCX-Cre/ER mice express a tamoxifen-inducible Cre recombinase from the mouse Dcx (doublecortin) gene in adult-born neurons of the subventricular zone and hippocampal subgranular zone.

型号：GM-J#038587 -Cryorecovery

应用：Foxi3CreER knock-in/knock-out mice have a CreER fusion protein driven by the Foxi3 endogenous promoter, while abolishing endogenous Foxi3 expression. This strain may be useful for Cre-lox studies of Foxi3-expressing cells during embryogenesis; specifically, neuroepithelial cells, pharyngeal arches and pouches, as well as hair and tooth progenitor cells. Although eGFP is also present in this Foxi3CreER allele, its low level of expression from the construct did not allow detection of the eGFP protein, either by native fluorescence or by immunostaining with GFP antibodies.

型号：GM-J#038582 -Cryorecovery

应用：Fbxo2CreERT2 knock-in/knock-out mice express a CreER fusion protein driven by the F-box protein 2 (Fbxo2) endogenous promoter, while abolishing endogenous Fbxo2 expression. When these mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated

型号：GM-J#038571 -Available For Pre-Order

应用：Inducible MCI-PARK mice, based on the ESR-NDUFS2 strain described by Fernández-Agüera, 2015 (PMID: 26437605), were generated through an intercross of mice carrying a floxed allele of mouse NADH:ubiquinone oxidoreductase core subunit S2 (Ndufs2; derived from Stock No. 036313) with animals that broadly express tamoxifen-inducible cre recombinase (Tg(CAG-cre/Esr1*)5Amc; Stock No. 004682). Induction with tamoxifen creates a conditional knock-out of Ndufs2, useful in studies of Parkinson’s disease (PD).

型号：GM-J#038528 -Available For Registering Interest

应用：ApoE-rtTA:TRE2-Cre mice are useful for the induction of cre expression in hepatocytes following doxycycline administration.

型号：GM-J#038515 -Available For Pre-Order

应用：GlyT2::Cre transgenic mice express Cre recombinase under the control of the murine Slc6a5 promoter. They may be useful for site-specific recombination in glycinergic neurons.

型号：GM-J#038514 -Available For Pre-Order

应用：GlyT2::CreERT2 transgenic mice express a cre/ERT2 fusion gene under the control of the murine Slc6a5 promoter. They may be useful for site-specific tamoxifen- inducible cre recombination in glycinergic neurons.