产品型号:GM-J#038571 -Available For Pre-Order
产品应用:Inducible MCI-PARK mice, based on the ESR-NDUFS2 strain described by Fernández-Agüera, 2015 (PMID: 26437605), were generated through an intercross of mice carrying a floxed allele of mouse NADH:ubiquinone oxidoreductase core subunit S2 (Ndufs2; derived from Stock No. 036313) with animals that broadly express tamoxifen-inducible cre recombinase (Tg(CAG-cre/Esr1*)5Amc; Stock No. 004682). Induction with tamoxifen creates a conditional knock-out of Ndufs2, useful in studies of Parkinson’s disease (PD).