型号：GM-J#023035 -Cryorecovery

应用：ROSAnT-nG mice are available on a congenic C57BL/6NJ background (Stock No. 023537) and the congenic version will replace this mixed background strain in the near future.

型号：GM-J#023014 -Cryorecovery

应用：These mice express Cre recombinase under the control of the murine calcitonin receptor-like (Calcrl) promoter. This strain represents an effective tool for generating mossy cell specific-targeted mutants.

型号：GM-J#022977 -Cryorecovery

应用：These TG11ML (MADM-ML-11TG) mice are designed for MADM (mosaic analysis with double markers), and must be crossed to mice harboring a reciprocal mutation at the same locus (GT11ML; Stock No. 022976). Compared to the single loxP approach of the original MADM designs, the multiple self-recognizing lox variant sites present in the MADM-ML system result in significantly improved recombination efficiency (4-8 fold higher) with no negative impact on G2-X segregation percentage (G2-X segregation produces the desired fluorescent homozygous mutant daughter cells). This MADM-ML system allows Cre and/or FLP recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation, mitosis, and imprinting.

型号：GM-J#022976 -Cryorecovery

应用：GT11ML (MADM-ML-11GT) mice are designed for MADM (mosaic analysis with double markers), and must be crossed to mice harboring a reciprocal mutation at the same locus (TG11ML; Stock No. 022977). Compared to the single loxP approach of the original MADM designs, the multiple self-recognizing lox variant sites present in the MADM-ML system result in significantly improved recombination efficiency (4-8 fold higher) with no negative impact on G2-X segregation percentage (G2-X segregation produces the desired fluorescent homozygous mutant daughter cells). This MADM-ML system allows Cre recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation, mitosis, and imprinting.

型号：GM-J#022887 -Cryorecovery

应用：These Six6-cre transgenic mice may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#022883 -Cryorecovery

应用：These Six6-cre transgenic mice may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#022880 -Cryorecovery

应用：These Lrrk1 knock-out mice may be useful for studying the role of Lrrk1 in the progression of Parkinson's Disease.

型号：GM-J#022865 -Cryorecovery

应用：Trib2-2A-CreERT2-D knockin/knockout mice express an inducible CreERT2 fusion protein from the endogenous tribbles homolog 2 promoter/enhancer elements. When induced, cre activity is observed in superficial layer 5 cortical neurons, other scattered cells throughout the cortex, and brain vasculature. Disruption of the Trib2 gene is presumed.

型号：GM-J#022864 -Cryorecovery

应用：Rasgrf2-2A-dCre mice express a trimethoprim-inducible Cre recombinase directed by endogenous Rasgrf2 promoter/enhancer elements. When induced, Cre recombinase activity is observed in cortical layers 2/3 and other scattered cells of the cortex, hypothalamus, thalamus, and midbrain.

型号：GM-J#022863 -Cryorecovery

应用：Pvalb-T2A-dCre-D (Pvalb-2A-dCre-D) mice express a trimethoprim-inducible Cre recombinase directed to Pvalb-expressing cells by the endogenous promoter/enhancer elements of the parvalbumin locus. When induced, Cre recombinase activity is observed in scattered cells throughout the cortex, as well as restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus.