型号:GM-J#022862 -Cryorecovery
应用:These knockin mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the preproenkephalin locus. When induced, cre activity is observed in the striatum, olfactory tubercle, and sparse cells in the dentate gyrus and cortex.
型号:GM-J#022861 -Cryorecovery
应用:These knockin mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the neurexophilin 4 locus. When induced, cre activity is observed in cortical layer 6b neurons and other scattered small cells [possibly glia] throughout the cortex.
型号:GM-J#022793 -Cryorecovery
应用:These ROSA26-LRRK2 (R1441C) mice allow cre-inducible expression of the familial Parkinson's disease-associated R1441C missense mutant form of LRRK2, and may be useful for studying Parkinson's disease pathogenesis and neurodegeneration.
型号:GM-J#022791 -Available
应用:These transgenic mice express cre recombinase under the control of the mouse Rorc (RAR-related orphan receptor gamma; also called RORγt) promoter. Expression can be found in double positive thymocytes and their CD4+ and CD8+ single positive progeny as well as all αβ T cells of the spleen and lymphoid tissue inducer cells (LTi) and RORG+ innate lymphoid cells.
型号:GM-J#022763 -Cryorecovery
应用:Nse-CreERT2 transgenic mice express the tamoxifen inducible cre/ERT2 fusion gene in cerebellar lobular granule cells and in a few hippocampal dentate gyrus granule cells as directed by the rat Eno2 (enolase 2, gamma, neuronal) promoter. Cre-ERT2 fusion gene activity is inducible by the administration of tamoxifen.
型号:GM-J#022757 -Cryorecovery
应用:These Prg4GFPCreERt2 mice express the inducible GFP/cre/ERT2 fusion gene in a pattern that mimics the expression of the endogenous Prg4 gene: in the chondrocytes of articular cartilage but not in the growth plate chondrocytes.
型号:GM-J#022731 -Cryorecovery
应用:These Ai62(TITL-tdT)-D mice (also called Ai62D) are a fluorescent Cre/Tet reporter line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). After removal of the floxed-STOP cassette by Cre recombinase, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of tdTomato.
型号:GM-J#022510 -Cryorecovery
应用:In this knock-in/knockout mutation, most of the Gpr88 (G-protein coupled receptor 88) open reading frame is replaced by a cre recombinase-EGFP fusion protein. Expression of GPR88 protein is ablated and EGFP and cre are constitutively driven from the endogenous striatum-specific promoter.
型号:GM-J#022390 -Cryorecovery
应用:These mice express Cre-ERT2 under the direction of the human caudal type homeo box 2 (CDX2) gene promoter/enhancer regions. They are useful when studying gene function in adult epithelium of the distal intestinal tract.
型号:GM-J#022367 -Cryorecovery
应用:fs-TRAP mice are designed to express the EGFP-L10a ribosome tag following exposure to Cre recombinase, and then express 2xHA-tagged BirA (biotin ligase) following exposure to FLP recombinase. This is a tool for the isolation and purification of ribosome-bound proteins and protein complexes from tissues.