型号:GM-J#022863 -Cryorecovery
应用:Pvalb-T2A-dCre-D (Pvalb-2A-dCre-D) mice express a trimethoprim-inducible Cre recombinase directed to Pvalb-expressing cells by the endogenous promoter/enhancer elements of the parvalbumin locus. When induced, Cre recombinase activity is observed in scattered cells throughout the cortex, as well as restricted populations in the cerebellum, medulla, pons, pallidum, and thalamus.
型号:GM-J#022862 -Cryorecovery
应用:These knockin mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the preproenkephalin locus. When induced, cre activity is observed in the striatum, olfactory tubercle, and sparse cells in the dentate gyrus and cortex.
型号:GM-J#022861 -Cryorecovery
应用:These knockin mice express a tamoxifen-inducible cre recombinase from the endogenous promoter/enhancer elements of the neurexophilin 4 locus. When induced, cre activity is observed in cortical layer 6b neurons and other scattered small cells [possibly glia] throughout the cortex.
型号:GM-J#022793 -Cryorecovery
应用:These ROSA26-LRRK2 (R1441C) mice allow cre-inducible expression of the familial Parkinson's disease-associated R1441C missense mutant form of LRRK2, and may be useful for studying Parkinson's disease pathogenesis and neurodegeneration.
型号:GM-J#022791 -Available
应用:These transgenic mice express cre recombinase under the control of the mouse Rorc (RAR-related orphan receptor gamma; also called RORγt) promoter. Expression can be found in double positive thymocytes and their CD4+ and CD8+ single positive progeny as well as all αβ T cells of the spleen and lymphoid tissue inducer cells (LTi) and RORG+ innate lymphoid cells.
型号:GM-J#022763 -Cryorecovery
应用:Nse-CreERT2 transgenic mice express the tamoxifen inducible cre/ERT2 fusion gene in cerebellar lobular granule cells and in a few hippocampal dentate gyrus granule cells as directed by the rat Eno2 (enolase 2, gamma, neuronal) promoter. Cre-ERT2 fusion gene activity is inducible by the administration of tamoxifen.
型号:GM-J#022757 -Cryorecovery
应用:These Prg4GFPCreERt2 mice express the inducible GFP/cre/ERT2 fusion gene in a pattern that mimics the expression of the endogenous Prg4 gene: in the chondrocytes of articular cartilage but not in the growth plate chondrocytes.
型号:GM-J#022731 -Cryorecovery
应用:These Ai62(TITL-tdT)-D mice (also called Ai62D) are a fluorescent Cre/Tet reporter line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). After removal of the floxed-STOP cassette by Cre recombinase, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of tdTomato.
型号:GM-J#022510 -Cryorecovery
应用:In this knock-in/knockout mutation, most of the Gpr88 (G-protein coupled receptor 88) open reading frame is replaced by a cre recombinase-EGFP fusion protein. Expression of GPR88 protein is ablated and EGFP and cre are constitutively driven from the endogenous striatum-specific promoter.
型号:GM-J#022390 -Cryorecovery
应用:These mice express Cre-ERT2 under the direction of the human caudal type homeo box 2 (CDX2) gene promoter/enhancer regions. They are useful when studying gene function in adult epithelium of the distal intestinal tract.