型号:GM-J#022357 -Cryorecovery
应用:These mice express Cre-ERT2 under the direction of the activity regulated cytoskeletal-associated protein (Arc) promoter/enhancer regions. They are useful in comparing activation of neuronal populations in the hippocampus during encoding and retrieval of memory.
型号:GM-J#022356 -Available
应用:This CD4CreERT2 mutant mouse strain, carrying a transgene with tamoxifen-inducible Cre recombinase under the control of the mouse Cd4 (CD4 antigen) promoter, may be useful for generating peripheral CD4 positive T cell specific targeted mutants and in studies of T cell development and differentiation.
型号:GM-J#022135 -Cryorecovery
应用:This strain expresses a CreERT2-IRES-EGFP cassette from the gastrulation brain homeobox 2 Gbx2 promoter/enhancer elements. These mice may be useful for lineage mapping of thalamic neuronal precursor cells.
型号:GM-J#022075 -Available
应用:Prox1-Cre-ERT2 mice express tamoxifen-inducible Cre recombinase in lymphatic endothelial cells.
型号:GM-J#022071 -Available Now
应用:CD4-Cre transgenic mice contain CD4 enhancer, promoter and silencer sequences driving the expression of a Cre recombinase gene. These mice may be useful for generating conditional mutations in CD4-expressing tissues.
型号:GM-J#021962 -Cryorecovery
应用:PITX3+/IRES2-tTA KI mice may be useful when studying the pathogenic mechanism of α-syn-dependent dopaminergic dysfunction.
型号:GM-J#021961 -Cryorecovery
应用:An internal ribosome entry site (IRES)-CreERT2 fusion protein and a polyadenylation signal were placed downstream of the endogenous stop codon of the ATP-binding cassette, sub-family G (WHITE), member 2 Abcg2 gene. These mice may be useful for hematopoietic lineage tracking.
型号:GM-J#021914 -Cryorecovery
应用:These Atp13a2 targeted mutation mice develop late-onset impaired motor function and behavior, as well as lipofuscinosis. This strain may be useful in studies related to synucleinopathies such as Parkinson's disease, and lysosomal storage disorders.
型号:GM-J#021913 -Cryorecovery
应用:These transgenic mice express a mutant human form of human leucine-rich repeat kinase 2 (LRRK2 ), containing an A->G transition (Y1699C), and may be useful in studies of Parkinson's disease.
型号:GM-J#021882 -Available
应用:The FosCreER knock-in/knockout allele was designed to both abolish expression of the Fos immediate early gene and direct expression of the CreERT2 fusion protein from the Fos promoter/enhancer elements. These mice are a Cre-lox tool that allows inducible Cre expression in Fos-expressing cells/tissues; including neurons activated by specific somatosensory, visual, and auditory stimuli. Immediate early genes (IEGs) are the connection between gene expression and a neuron's electrical/synaptic activity (which defines the neuron's response properties).