型号：GM-J#006230 -Cryorecovery

应用：These mice express an interferon or synthetic double-stranded RNA inducible Cre recombinase. When induced, Cre recombinase activity is observed in hematopoietic tissue.

型号：GM-J#006224 -Cryorecovery

应用：Tetracycline inducible, tissue specific-targeted mutants can be generated by breeding hemizygotes of this strain with other transgenic mice that express transactivator proteins under the control of tissue-specific promoters.

型号：GM-J#006207 -Cryorecovery

应用：In these transgenic mice the L7/Pcp2 modified promoter directs tissue specific expression of cre in cerebellar Purkinje cells. A co-integrated GFP transgene results in GFP expression in the cerebellum.

型号：GM-J#006149 -Available

应用：These transgenic mice have the cre recombinase gene driven by the human alpha-skeletal actin (HSA or ACTA1) promoter. When bred with mice containing a loxP-flanked sequence of interest, Cre-mediated recombination will result in striated muscle-specific deletion of the flanked genome. These mice are useful in study of spinal muscular atrophy (SMA).

型号：GM-J#006148 -Available Now

应用：These R26-stop-EYFP mutant mice have a loxP-flanked STOP sequence followed by the Enhanced Yellow Fluorescent Protein gene (EYFP) inserted into the Gt(ROSA)26Sor locus. When bred to mice expressing Cre recombinase, the STOP sequence is deleted and EYFP expression is observed in the cre-expressing tissue(s) of the double mutant offspring. These mutant mice may be useful in monitoring the Cre expression in living tissues, and tracing the lineage of such cells in embryos, young, and adult mice at desired time points.

型号：GM-J#006143 -Cryorecovery

应用：Cre expression is driven in neurons of the postnatal cortex and hippocampus of hemizygous mice. These mice may be useful in studies of the nervous system, including Alzheimer's disease.

型号：GM-J#006139 -Cryorecovery

应用：These transgenic mice have the cre recombinase gene driven by the human alpha-skeletal actin (HSA or ACTA1) promoter. When bred with mice containing a loxP-flanked sequence of interest, Cre-mediated recombination will result in striated muscle-specific deletion of the flanked genome. These mice are useful in study of spinal muscular atrophy (SMA).

型号：GM-J#006137 -Available

应用：Cre expression in these transgenic mice can be seen in the embryo and in adult endothelium of developing and quiescent vessels, as well as in a subset of hematopoietic cells. When bred with mice carrying a loxP-flanked sequence of interest, Cre-mediated recombination will result in deletion of the flanked genome. These mice may be useful in studies of the cardiovascular system.

型号：GM-J#006084 -Cryorecovery

应用：mice express Cre recombinase from the endogenous Foxg1 locus specifically in the telencephalon and discrete head structures. Heterozygotes exhibit disruption of forebrain development, resulting in reduction in the volume of the neocortex, hippocampus and striatum. When crossed with a strain containing a floxed gene of interest, Cre-mediated recombination is observed in the telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches. These mice may be useful in studies of telencephalic development.

型号：GM-J#006080 -Cryorecovery

应用：These knock-in mice were developed to utilize the mosaic analysis with double markers (MADM) system that allows simultaneous labeling and gene knockout in clones of somatic cells or isolated single cells in vivo. This strain carries the red fluorescent protein, Dsred2 (R) and the green fluorescent protein, EGFP (G) as markers to be used in conjunction with strains carrying the reciprocal chimeric marker genes (MADM-GR).