产品型号:GM-J#006084 -Cryorecovery
产品应用:mice express Cre recombinase from the endogenous Foxg1 locus specifically in the telencephalon and discrete head structures. Heterozygotes exhibit disruption of forebrain development, resulting in reduction in the volume of the neocortex, hippocampus and striatum. When crossed with a strain containing a floxed gene of interest, Cre-mediated recombination is observed in the telencephalon, anterior optic vesicle, otic vesicle, facial and head ectoderm, olfactory epithelium, mid-hindbrain junction and pharyngeal pouches. These mice may be useful in studies of telencephalic development.