型号:GM-J#006390 -Cryorecovery
应用:These double-knockout mice for alpha and beta-synucleins exhibit decreased dopamine levels and are useful in studies of synaptic function and neurodegeneration.
型号:GM-J#006368 -Cryorecovery
应用:Mice from CD21-cre BAC transgenic line 3a (CD21-cre3a) have Cre recombinase expression directed to mature B cells and follicular dendritic cells. Cre recombinase expression is also observed in forebrain, uterus, ovary, heart, kidney and testes. CD21-cre3a mice are a Cre-lox tool strain useful for studying B lymphocyte development.
型号:GM-J#006364 -Cryorecovery
应用:These transgenic mice display Cre recombinase activity in SF1-expressing neurons in the hypothalamus, pituitary, gonad, and adrenal tissue.
型号:GM-J#006361 -Available
应用:Cre-mediated recombination in these mice is under control of doxycycline, and in its absence EGFP-Cre fusion protein expression is restricted to the osteoblast lineage throughout embryonic and early postnatal development. When mated to floxed transgenic strains, administration of doxycycline prevents fusion protein expression and recombination. These Osx1-GFP::Cre mutant mice may be useful in studies of bone development, osteoblast lineage and Hedgehog/Wnt signaling.
型号:GM-J#006340 -Cryorecovery
应用:GFP in these X98 transgenic mice is expressed in Martinotti neurons of the neocortex.
型号:GM-J#006333 -Cryorecovery
应用:Cre expression in these mice is observed in islets of the adult pancreas, small intestine enteroendocrine cells, endocrine portions of the stomach, all pancreatic endocrine cells, and in some non-endocrine intestinal cells. When bred with a mouse containing a loxP site-flanked sequence of interest, Cre-mediated recombination results in deletion of the flanked gene in the tissues that normally express neurogenin 3.
型号:GM-J#006302 -Not Available At Jax
应用:These dopamine transporter IRES-cre (DATIREScre) mutant mice exhibit co-localization of Cre recombinase and endogenous Slc6a3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3) gene expression and may be useful in neurobiological studies to facilitate the analysis of gene function in
型号:GM-J#006297 -Cryorecovery
应用:These transgenic mice harbor a Cre recombinase gene under the control of the rat neuron specific enolase (NSE or Eno2) gene, directing Cre recombinase activity to neurons with expression in many tissue types. These mice may also be useful in studies of spinal muscular atrophy (SMA) .
型号:GM-J#006244 -Cryorecovery
应用:Tetracycline inducible, tissue specific-targeted mutants can be generated by breeding hemizygotes of this strain with other transgenic mice that express transactivator proteins under the control of tissue-specific promoters.
型号:GM-J#006234 -Available
应用:These transgenic mice express Cre recombinase under the control of a tetracycline-responsive promoter element (TRE or tetO) and are an effective tool for generating inducible, tissue-specific, targeted mutants to study cell lineage during development. When bred with another transgenic mouse expressing reverse tetracycline-controlled transactivator protein (rtTA) or tetracycline-controlled transactivator protein (tTA), Cre mediated recombination in the resulting bitransgenic offspring can be regulated with the tetracycline analog, doxycycline.