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  • 型号:GM-J#005650 -Cryorecovery

    应用:The alpha-MHC-MerCreMer (αMHC-MerCreMer) transgene has the mouse cardiac-specific alpha-myosin heavy chain promoter (αMHC or alpha-MHC; Myh6) directing expression of a tamoxifen-inducible Cre recombinase (MerCreMer) to juvenile and adult cardiac myocytes. These αMHC-MerCreMer transgenic mice allow the creation of bitransgenic mice for Cre-lox studies of temporally regulated deletion of loxP-flanked targeted genes in cardiac tissues/cells.

    2024-11-09 点击次数:3

    型号:GM-J#005630 -Cryorecovery

    应用:These Thy1-STOP-YFP mice possess loxP sites flanking the STOP codon between the promoter and EYFP gene. When bred to mice carrying cre recombinase EYFP will be expressed in motor neurons.

    2024-11-09 点击次数:2

    型号:GM-J#005628 -Available

    应用:Emx1-IRES-Cre knock-in mice have the endogenous Emx1 locus directing expression of Cre recombinase to approximately 88% of the neurons of the neocortex and hippocampus, and in the glial cells of the pallium. These mice are useful in studies of forebrain development and function.

    2024-11-09 点击次数:1

    型号:GM-J#005623 -Available

    应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

    2024-11-09 点击次数:2

    型号:GM-J#005622 -Available

    应用:Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

    2024-11-09 点击次数:3

    型号:GM-J#005584 -Available

    应用:Prx1-Cre (Prrx1Cre) transgenic mice have the Prrx1 promoter/enhancer directing Cre recombinase expression to early limb bud mesenchyme and a subset of craniofacial mesenchyme. This tool strain may be useful for generating tissue specific-targeted mutants for studying limb bud development and patterning.

    2024-11-09 点击次数:3

    型号:GM-J#005572 -Cryorecovery

    应用:After breeding with mice carrying Cre recombinase, rtTA and EGFP are expressed in the tissues that express cre in the offspring.

    2024-11-09 点击次数:2

    型号:GM-J#005549 -Cryorecovery

    应用:Cre recombinase expression is detected in the dorsal neural tube and somites of early embryos and in neural crest and somite derivatives of later gestation embryos. This knock-in mutant mouse strain represents a model that may be useful in studies of development and lineage mapping of neural crest and somite derivatives

    2024-11-09 点击次数:3

    型号:GM-J#005438 -Cryorecovery

    应用:These Z/RED transgenic mice express beta-galactosidase (lacZ) under the control of the chicken beta actin promoter coupled with the cytomegalovirus (CMV) immediate early enhancer. When crossed with a Cre recombinase-expressing strain, lacZ expression is replaced with red fluorescent protein (DsRed*MST) expression in tissues expressing Cre recombinase. This double reporter system makes it possible to distinguish a lack of reporter expression from a lack of Cre recombinase expression while providing a means to assess Cre excision activity in live animals and cells.

    2024-11-09 点击次数:2

    型号:GM-J#005359 -Available

    应用:This strain is commonly known as T29-1. CaMKIIα-Cre line T29-1 transgenic mice have the mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a) promoter driving Cre recombinase expression in the forebrain, including the CA1 pyramidal cell layer of the hippocampus. See strain description below for additional information. This strain is useful is examining synaptic plasticity and Long Term Potentiation (LTP) in hippocampal networks.

    2024-11-09 点击次数:6
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