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  • B6.Cg-Tg(Sp7-tTA,tetO-EGFP/cre)

    产品型号:GM-J#006361 -Available

    产品应用:Cre-mediated recombination in these mice is under control of doxycycline, and in its absence EGFP-Cre fusion protein expression is restricted to the osteoblast lineage throughout embryonic and early postnatal development. When mated to floxed transgenic strains, administration of doxycycline prevents fusion protein expression and recombination. These Osx1-GFP::Cre mutant mice may be useful in studies of bone development, osteoblast lineage and Hedgehog/Wnt signaling.

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