型号：GM-J#009606 -Cryorecovery

应用：Six2-TGCtg mice express an EGFPCre fusion protein directed to nephron progenitor population cap mesenchyme from the onset of metanephric kidney development by the Six2 (sine oculis-related homeobox 2 homolog (Drosophila)) promoter/enhancer regions within the ~181 kb BAC transgene. These Six2-TGCtg mice may be useful as fluorescent or Cre-lox tools for lineage-tracing/marking Six2-expressing cells for studying multipotent nephron progenitor cell populations throughout kidney organogenesis.

型号：GM-J#009604 -Cryorecovery

应用：In response to numerous reports questioning the hypokinetic phenotype of this strain, The Jackson Laboratory initiated behavioral testing on a cohort of 12 month old hemizygous FVB/N-Tg(LRRK2*R1441G)135Cjli/J and age matched controls. To date, we have been unable to validate the hypokinetic motor deficits reported for this strain. We have verified the transgene is expressed.

型号：GM-J#009600 -Cryorecovery

应用：This Six2GCE knock-in/knock-out allele was designed to both abolish Six2 gene function and express EGFP and creERT2 from the Six2 promoter/enhancer elements. While EGFP expression is observed in nephron progenitor population cap mesenchyme from the onset of metanephric kidney development, Cre-ERT2 fusion gene activity is inducible observed in the same cells only following tamoxifen administration. These Six2GCE mice may be useful for lineage-tracing/marking Six2-expressing cells for studying multipotent nephron progenitor cell populations throughout kidney organogenesis.

型号：GM-J#009585 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009584 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009583 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009582 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009581 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009580 -Cryorecovery

应用：These mice express the Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

型号：GM-J#009579 -Cryorecovery

应用：These mice express the tamoxifen-inducible Cre-ERT2 fusion protein (Cre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.