产品型号:GM-J#009600 -Cryorecovery
产品应用:This Six2GCE knock-in/knock-out allele was designed to both abolish Six2 gene function and express EGFP and creERT2 from the Six2 promoter/enhancer elements. While EGFP expression is observed in nephron progenitor population cap mesenchyme from the onset of metanephric kidney development, Cre-ERT2 fusion gene activity is inducible observed in the same cells only following tamoxifen administration. These Six2GCE mice may be useful for lineage-tracing/marking Six2-expressing cells for studying multipotent nephron progenitor cell populations throughout kidney organogenesis.