型号：GM-J#010559 -Cryorecovery

应用：These mice possess loxP sites on either side of the Pou4f2 (POU domain, class 4, transcription factor 2) coding region followed by an alkaline phosphatase reporter. When crossed with a cre recombinase-expressing strain, the offspring express AP in the retina, several brain nuclei, dorsal root ganglia, trigeminal ganglion, and other cells/tissues.

型号：GM-J#010558 -Cryorecovery

应用：These mice possess loxP sites on either side of the Pou4f1 (POU domain, class 4, transcription factor 1) coding region followed by an alkaline phosphatase (AP) reporter. When crossed with a cre recombinase-expressing strain, offspring express AP in the retina, several brain nuclei, dorsal root ganglia, trigeminal ganglion, and other cells/tissues.

型号：GM-J#010557 -Cryorecovery

应用：These R26rtTACreER mice have a CreERT, reverse tetracycline trans-activator (rtTA), and Tet-responsive element (TRE) targeted to the mouse Gt(ROSA)26Sor gene to create a gene expression tool with two independent layers of pharmacologic control and a widespread pattern of activity. In this construct, expression of tamoxifen-sensitive CreERT is under the control of rtTA. Upon administration of doxycycline, rtTA activates transcription of the CreER coding region. This enhances the dynamic range of CreER and enables sparse labeling in situations where reduced recombination efficiency facilitates behavioral, morphological or functional studies of modified cells among populations of unmodified neighbors.

型号：GM-J#010550 -Cryorecovery

应用：The mouse Penk (preproenkephalin) promoter drives expression of the C. elegans glutamate-gated chloride channel beta subunit and cre/ESR1. When crossed with a strain containing a loxP site-flanked sequence of interest, the flanked sequences are deleted in the offspring upon administration of tamoxifen.

型号：GM-J#010536 -Available

应用：These transgenic mice express Cre recombinase under the control of the mouse Purkinje cell protein (Pcp2). Cre recombinase expression is detected in Purkinje cells of the cerebellar folia and retinal bipolar cells. This strain represents an effective tool for generating tissue specific-targeted mutants that would be useful in neurological research.

型号：GM-J#010531 -Cryorecovery

应用：These targeted mutant mice carry tamoxifen-inducible Cre under the transcriptional control of the mouse Bmi1 (Bmi1 polycomb ring finger oncogene) promoter. When crossed with a strain containing a loxP-flanked sequence of interest, the offspring are useful for generating tamoxifen-induced, Cre-mediated targeted deletions, and when crossed with a floxed reporter strain, lineage tracing of Bmi1-expressing cells is possible.

型号：GM-J#010530 -Cryorecovery

应用：This Pax7 knock-in strain may be useful in studies of alveolar rhabdomyosarcoma and embryonic myogenesis.

型号：GM-J#010529 -Cryorecovery

应用：In this strain, the mouse myogenic factor 5 (Myf5) promoter drives expression of both the targeted gene and cre in myoblast progenitors of skeletal muscle lineage and some cartilage progenitors in the ribs. Crossing this mouse with another carrying a loxP-flanked genomic segment of interest enables tissue-specific excision of the floxed segment in the offspring.

型号：GM-J#010528 -Cryorecovery

应用：In this strain, the mouse myogenic factor 6 (Myf6) promoter drives expression of both the targeted gene and cre in differentiated myocytes of skeletal muscle lineage. When crossed with a strain carrying a loxP-flanked genomic segment of interest, tissue-specific excision of that segment may be achieved in the offspring.

型号：GM-J#010523 -Cryorecovery

应用：These mice contain (STOP-hPLAP): the human alkaline phosphatase, placental (Regan isozyme), ALPP, gene under the control of the CAG (chicken beta actin promoter/enhancer and cytomegalovirus immediate-early enhancer) promoter, inserted into the Gt(ROSA)26Sor locus. Expression of the ALPP gene is blocked by a loxP-flanked STOP fragment placed between the ALPP sequence and the Gt(ROSA)26Sor promoter. This strain serves as a reporter strain, with successful Cre-mediated excision being indicated by ALPP expression in cre-expressing tissues.