型号:GM-J#024384 -Cryorecovery
应用:bAMG-Cre mice express Cre recombinase in ameloblsts under the direction of the X-linked bovine amelogenin promoter.
型号:GM-J#024355 -Cryorecovery
应用:These mice carry a spontaneous neurological mutation (nm3419) in the Uchl1 gene that results in progressive motor defects, weight loss and early homozygous lethality by approximately 200 days of age.
型号:GM-J#024341 -Cryorecovery
应用:These c-Relfl mutant mice possess loxP and FRT sites flanking exon 1 of the Rel gene. This strain may be useful for generating conditional mutations in applications related to the NF-kB signal transduction pathway. Cre-mediated recombination also results in expression of GFP (Green Fluorescent Protein) which can be used to trace Rel ablation.
型号:GM-J#024338 -Cryorecovery
应用:These SNCA-A30P mice express a transgene containing a mutant human SNCA gene and are suitable for use in applications related to the study of Parkinson's disease.
型号:GM-J#024283 -Cryorecovery
应用:HCN4CreERT2 mice express CreERT2 in the first heart field of differentiating myocytes in the developing cardiac crescent.
型号:GM-J#024244 -Cryorecovery
应用:This allele generates tri-cistronic expression from the Gucy1b2 locus of the endogenous Gucy1b2 gene, cre recombinase with a nuclear localization signal, and a tauLacZ reporter, each separated from the next by an IRES sequence. This provides cre expression in cells expressing GUCY1B2 and marked by tauLacZ expression.
型号:GM-J#024242 -Cryorecovery
应用:Isl1Cre mice express Cre recombinase under the control of the ISL1 transcription factor, LIM/homeodomain promoter and are an effective tool for studying heart and limb abnormalities.
型号:GM-J#024240 -Cryorecovery
应用:cTntCre mice express Cre recombinase under the control of the rat troponin T2, cardiac promoter. This strain represents an effective tool for generating early cardiomyocyte specific-targeted mutants that would be useful in studies of human congenital heart abnormalities.
型号:GM-J#024234 -Available
应用:These mice express Cre recombinase under the control of the oxytocin promoter and are an effective tool for specifically targeting oxytocin neurons.
型号:GM-J#024115 -Cryorecovery
应用:Ai94(TITL-GCaMP6s)-D;CaMK2a-tTA (or Ai94D;CaMK2a-tTA) mice have a Cre/Tet-dependent, fluorescent calcium indicator GCaMP6s inserted into the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated), as well as a transgene directing tetracycline-controlled transactivator protein (tTA) expression in forebrain neurons. After removal of the floxed-STOP cassette by Cre recombinase, resulting mice have doxycycline-inducible/reversible expression of GCaMP6 slow variant calcium indicator (GCaMP6s; an ultrasensitive detector of single neuronal action potentials with slower decay and response kinetics). Following subsequent calcium binding (such as neuronal activation), increased EGFP fluorescence is observed in those cells.