型号:GM-J#024574 -Cryorecovery
应用:These Gba*L444P mice contain a mutation in the Gba1 gene, similar to that found in humans with Gaucher disease and Parkinson's disease.
型号:GM-J#024564 -Cryorecovery
应用:The ΔNp63Cre allele expresses Cre Recombinase from the Trp63 promoter/enhancer elements in epithelial cells. These mice may be useful for genetic lineage tracing of ΔNp63-expressing cells of the caudal endoderm in vivo.
型号:GM-J#024529 -Cryorecovery
应用:This PLZFGFPcre reporter strain incorporates an IRES-EGFPcre fusion protein expressed from the mouse PLZF/Zbtb16 promoter. EGFP and Cre recombinase are expressed in the NKT cell lineage.
型号:GM-J#024521 -Cryorecovery
应用:These mice carry a targeted mutation in which exons 24 through 28 are deleted. Mutations in Eif4g1, a translation initiation factor, are associated with susceptibility to Parkinson's disease.
型号:GM-J#024511 -Cryorecovery
应用:HEBf E2Af mice allow Cre-recombinase inducible deletion of the two basic helix-loop-helix (bHLH) E-protein family genes HEB and E2A. These mice may be useful for studying B and T lymphocyte development and lymphoid malignancies.
型号:GM-J#024507 -Cryorecovery
应用:These transgenic mice express Cre recombinase from the mouse Tbx21 (T-box 21; also called Tbet) promoter in mitral cells of the main and accessory olfactory bulbs.
型号:GM-J#024477 -Cryorecovery
应用:PC::G5-tdT mice express the fluorescent calcium indicator protein GCaMP5G variant and tdTomato red fluorescent protein in a Cre recombinase inducible system. Increases in intracellular calcium (such as through neuronal activation) leads to bright GCaMP5G fluorescence. PC::G5-tdT is suitable for use in applications related to functional imaging of activity in neurons, astrocytes and microglia.
型号:GM-J#024475 -Cryorecovery
应用:These MyoDCE/CE knock-in mice express a cre/ERT fusion protein and TVA (avian leukosis virus receptor) in Myod1 expressing cells. These mice may have applications in studies requiring conditional gene manipulation in activated muscle satellite cells and myoblasts.
型号:GM-J#024474 -Cryorecovery
应用:These mice express Cre recombinase under the control of the murine interleukin 9 promoter in the lungs during airway inflammation.
型号:GM-J#024469 -Cryorecovery
应用:These mice possess loxP sites on either side of exon 41 of the Lrrk2 gene. This strain may be useful for generating conditional mutations suitable for use in applications related to the study of dendritic neuronal arborization and Parkinson's disease.