型号：GM-J#025533 -Cryorecovery

应用：These double mutant mice carry a targeted mutation for the Snca (synuclein, alpha) gene and a transgene consisting of the human SNCA under the direction of a mouse Thy-1 promoter. Applications exist in studies related to Parkinson's disease and neurodegeneration elicited by the aggregation of SNCA.

型号：GM-J#025524 -Available

应用：Cx3cr1-Cre mice express Cre recombinase under the direction of the Cx3cr1 promoter in the mononuclear phagocyte system making them useful for fate-mapping studies of the monocyte and macrophage compartment, as well as microglia. These mice do not express endogenous Cx3cr1.

型号：GM-J#025523 -Cryorecovery

应用：These mice express a codon improved Cre-recombinase in conventional dendritic cell precursors and may be useful for dendritic cell lineage fate mapping.

型号：GM-J#025521 -Cryorecovery

应用：Rax-CreERT2 mice express tamoxifen-inducible Cre recombinase under the direction of the Rax promoter. They are suitable for fate-mapping analysis in the developing and mature retina, hypothalamus and pituitary.

型号：GM-J#025520 -Cryorecovery

应用：These mice express Cre-ERT2 under the direction of the T promoter amaking them useful for applications requiring tamoxifen-induced deletion of floxed sequences during axis extension and somitogenesis.

型号：GM-J#025330 -Cryorecovery

应用：A copy number variation on human chromosome 16p11.2 is among the most common genetic variations found in autism spectrum disorders. 16p11flx mice are a Cre or FLP recombinase-inducible mouse model of 16p11.2 deletion that has several loxP and frt sites flanking the corresponding 440 kbp region on mouse chromosome 7F3. These mice may be useful in studying basal ganglia circuitry and the pathophysiology of autism.

型号：GM-J#025209 -Cryorecovery

应用：The Spp2G2aCE knock-in/knock-out allele was designed to both abolish Spp2 gene expression and express EGFP and Cre-ERT2 proteins from the Spp2 promoter in proximal tubule cells of the mouse kidney.

型号：GM-J#025208 -Cryorecovery

应用：The Entpd5G2aCE knock-in allele was designed to both abolish Entpd5 gene expression and express EGFP and Cre-ERT2 proteins from the Entpd5 promoter in proximal tubule cells of the mouse kidney.

型号：GM-J#025124 -Available

应用：These transgenic mice express a tamoxifen-inducible codon-improved Cre recombinase, iCre-ERT2, under the control of the Adipoq gene promoter. They may be useful in generating adipocyte-specific targeted mutants in studies related to adipose tissue function and storage, obesity, and other metabolic diseases.

型号：GM-J#025112 -Available

应用：Penk-IRES2-Cre knockin mice have Cre recombinase expression from the endogenous promoter/enhancer elements of the preproenkephalin locus. Cre recombinase activity is enriched in layers 2 and 6 of cortex and in restricted populations within olfactory areas, hippocampal formation, striatum, pallidum and hypothalamus. Scattered expression is also observed in thalamus, midbrain, pons, medulla, and cerebellum.