产品型号：GM-J#036061 -Cryorecovery

产品应用：These loxP-BphP1 mice are a Cre-dependent, Tet-controllable optogenetic line, created by targeted insertion of a CAG promoter, loxP-flanked EGFP-polyA cassette and the photoreceptor/fluorescent/tet-repressor fusion protein (RpBphP1/mCherry/TetR) into the the Gt(ROSA)26Sor locus. Widespread EGFP expression is replaced by RpBphP1/mCherry/TetR fusion protein expression upon Cre recombinase exposure. Further introduction of a BphP1 binding partner::nuclear-localization tag::VP16 activation domain construct and a tetO (TRE) promoter-driven reporter gene allow the subsequent control of reporter gene expression via illumination with near-infrared (NIR) light (~740-780 nm) as well as tetracycline/doxycycline.