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  • 型号:GM-J#012735 -Cryorecovery

    应用:The Ai35D (or Ai35Δneo) allele has a floxed-STOP cassette preventing transcription of the downstream Arch-GFP fusion gene. Exposure to Cre recombinase that deletes the STOP cassette results in Arch-GFP expression. These Ai35D mice are useful for optogenetic studies to express an inhibitory opsin that effectively silences the activity of cortical neurons (and perhaps other excitable cell types such as muscle cells and immune cells).

    2024-11-09 点击次数:1

    型号:GM-J#012710 -Cryorecovery

    应用:The Cck-CreER (or Cck-CreERT2) knock-in allele both abolishes cholecystokinin (Cck) gene function and expresses the CreERT2 fusion protein in cholecystokinin positive cortical neurons (both interneurons and pyramidal neurons) as directed by the endogenous Cck promoter/enhancer elements. Cre-ERT2 fusion gene activity is inducible by the administration of tamoxifen.

    2024-11-09 点击次数:0

    型号:GM-J#012708 -Available

    应用:These SLICK-H transgenic mice have expression of a CreERT2 fusion protein and an enhanced yellow fluorescent protein (EYFP) directed by two separate copies of the modified mouse Thy1 promoter region. These SLICK-H transgenic mice allow fluorescent labeling in the majority of projection neurons populations in the central and peripheral nervous system, with inducible Cre-lox genetic manipulation in the same widespread population of labeled neurons.

    2024-11-09 点击次数:0

    型号:GM-J#012706 -Available

    应用:The Cck-IRES-Cre knock-in allele has an internal ribosome entry site and Cre recombinase in the 3' UTR of the cholecystokinin locus (Cck). As such, Cre recombinase expression is directed to Cck-expressing cells (cholecystokinin positive neurons) by the endogenous promoter/enhancer elements of the cholecystokinin locus.

    2024-11-09 点击次数:0

    型号:GM-J#012704 -Available

    应用:CRH-ires-CRE knock-in mice have Cre recombinase expression directed to CRH positive neurons by the endogenous promoter/enhancer elements of the corticotropin releasing hormone locus (Crh).

    2024-11-09 点击次数:0

    型号:GM-J#012694 -Cryorecovery

    应用:These mice express the tamoxifen-inducible iCre-ERT2 fusion protein (iCre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

    2024-11-09 点击次数:0

    型号:GM-J#012693 -Cryorecovery

    应用:These mice express the tamoxifen-inducible iCre-ERT2 fusion protein (iCre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

    2024-11-09 点击次数:0

    型号:GM-J#012692 -Cryorecovery

    应用:These mice express the tamoxifen-inducible iCre-ERT2 fusion protein (iCre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

    2024-11-09 点击次数:0

    型号:GM-J#012691 -Cryorecovery

    应用:These mice express the tamoxifen-inducible iCre-ERT2 fusion protein (iCre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

    2024-11-09 点击次数:0

    型号:GM-J#012690 -Cryorecovery

    应用:These mice express the tamoxifen-inducible iCre-ERT2 fusion protein (iCre-ERT2) under the control of the promoter/enhancer regions surrounding the site where the enhancer trap transgene randomly inserted. These mice may be useful for generating conditional mutations for studying gain or loss of function and/or fate mapping in brain tissues.

    2024-11-09 点击次数:0
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