型号：GM-J#014541 -Cryorecovery

应用：The nNOS-CreER-KI knock-in allele was designed to both abolish neuronal nitric oxide synthase 1 (Nos1) gene function and direct CreERT2 fusion protein expression to nNOS positive GABAergic neurons by the endogenous Nos1 promoter/enhancer elements. Cre-ERT2 fusion gene activity is inducible by tamoxifen administration.

型号：GM-J#014539 -Available

应用：These Ai39 mice conditionally express an improved Halorhodopsin/EYFP fusion protein from the endogenous Gt(ROSA)26Sor locus. Following Cre-mediated removal of the STOP cassette, EYFP expression is observed in the cre-expressing cells. Subsequent illumination of these cells with yellow-to-red light leads to reversible photoinhibition of action potential firing/neural activity in these cells. These Ai39 mice are useful for optogenetic studies to express an inhibitory opsin that effectively silences the activity of cortical neurons.

型号：GM-J#014538 -Cryorecovery

应用：A C57BL/6J congenic version of this Ai38 strain will remain available as Stock No. 029043).

型号：GM-J#014180 -Cryorecovery

应用：This Myocd-Cre knock-in mutation strain may be useful for generating conditional mutations for studying fate mapping of early skeletal muscle lineages.

型号：GM-J#014160 -Cryorecovery

应用：This S100b-GCE transgenic strain expresses GFP and tamoxifen inducible Cre recombinase in developing bone and dorsal root ganglia and may be useful in studies of genitourinary development.

型号：GM-J#014159 -Cryorecovery

应用：This Tmem100-GCE transgenic strain expresses GFP and tamoxifen inducible Cre recombinase in the developing kidney and reproductive tracts and may be useful in studies of genitourinary development.

型号：GM-J#014140 -Cryorecovery

应用：This Myod1 knock-in strain may be useful for generating deletion mutants for lineage analysis and skeletal muscle-specific gene ablation.

型号：GM-J#014099 -Cryorecovery

应用：These transgenic mice have the murine pro-melanin-concentrating hormone (Pmch or MCH) promoter/enhancer regions within the BAC transgene directing expression of Cre-recombinase. These mice may be useful for studying MCH-neuronal activities in controlling energy balance, glucose homeostasis, sleep, locomotion, and reward-related behaviors.

型号：GM-J#014094 -Available

应用：These Sox2Cre transgenic mice express Cre recombinase under the control of the mouse Sox2 promoter, and may be useful for generating epiblast-derived specific conditional mutations.

型号：GM-J#013751 -Cryorecovery

应用：The MADM-11TG allele with enhanced green fluorescent protein is inserted into the Igs2 (formerly Hipp11) locus on chromosome 11. This MADM system allows Cre- or FLP-mediated fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation and mitosis.