型号：GM-J#018895 -Cryorecovery

应用：These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#018867 -Cryorecovery

应用：In this inducible Axin2 (axin2) knock-in/knockout strain, Cre-ERT2 protein expression affects cells with active Wnt/β-catenin pathway signaling. Crosses with floxed reporter strains enable conditional stem cell-specific labeling.

型号：GM-J#018829 -Cryorecovery

应用：These transgenic mice express an inducible version of cre recombinase mice under the direction of a Sox9 promoter. They are suitable for performing cre-recombination in pancreatic ductal cells and their progenitors.

型号：GM-J#018792 -Cryorecovery

应用：These Trp63-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by transformation related protein 63 (Trp63) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#018788 -Cryorecovery

应用：This strain expresses tamoxifen-inducible cre/ERT2 in high levels in mature olfactory sensory neurons and mature vomeronasal sensory neurons. It is valuable for the inducible expression or deletion of loxP-flanked alleles or reporters specifically in these neurons.

型号：GM-J#018786 -Cryorecovery

应用：Mice hemizygous for the BAC LRRK2(R1441G) transgene are viable and fertile, with expression of a mutant form of human leucine-rich repeat kinase 2 (LRRK2*R1441G) associated with autosomal dominant, late-onset Parkinson's disease directed by the human LRRK2 promoter/enhancer regions on the BAC transgene. These LRRK2(R1441G) mice represent an in vivo model for studying the Parkinson's disease pathogenesis and neurodegeneration elicited by the dominant toxic effects of mutant LRRK2(R1441G) expression.

型号：GM-J#018785 -Available Now

应用：Mice hemizygous for the BAC LRRK2 (G2019S) transgene express a mutant form of human leucine-rich repeat kinase 2 (LRRK2*G2019S) associated with autosomal dominant, late-onset Parkinson's disease directed by the human LRRK2 promoter/enhancer regions on the BAC transgene. These mice represent an in vivo model for studying the dominant toxic effects of mutant LRRK2*G2019S expression.

型号：GM-J#018768 -Cryorecovery

应用：These transgenic mice express the mutant human SNCA, synuclein, alpha (non A4 component of amyloid precursor), with the E46K mutation in exon 3, and may be useful in studies of Parkinson's Disease.

型号：GM-J#018683 -Cryorecovery

应用：These Wnt11-myrTagRFP-IRES-CE transgenic mice utilize a tamoxifen inducible Cre-mediated recombination system and may be useful in studies of genitourinary system development.

型号：GM-J#018682 -Cryorecovery

应用：These Meox1-nucTagRFP-T-IRES-CE transgenic mice utilize a tamoxifen inducible Cre-mediated recombination system and may be useful in studies of genitourinary system development.