型号:GM-J#018974 -Cryorecovery
应用:The Cre recombinase/green fluorescent protein fusion protein, driven by the Nr4a1 (Nur77) promoter in these mice, is expressed mainly in a subset of myeloid lineage cells of the spleen. These mice may be useful in studying thymocyte positive- and negative-selection as well as lymphocyte activation.
型号:GM-J#018973 -Available
应用:Sst-IRES-Cre knock-in mice express Cre recombinase in somatostatin-expressing neurons. These mice may be useful in studying dendritic inhibitory interneurons such as Martinotti cells and Oriens-Lacunosum-Moleculare cells.
型号:GM-J#018972 -Cryorecovery
应用:The cardiac-specific alpha myosin-heavy chain (Myh6) promoter drives expression of Cre recombinase in this alphaMhc-Cre transgenic strain. The promoter induces greater than 90% recombination in cardiac muscle cells.
型号:GM-J#018968 -Cryorecovery
应用:Vav-iCre transgenic mice have the mouse HS21/45 control regions directing expression of an optimized variant of Cre recombinase (iCre) to hematopoietic cells (and their progenitors), and may be useful for generating conditional mutations in hematopoietic cells.
型号:GM-J#018967 -Cryorecovery
应用:Mice harboring the Itgax-cre (Cd11c-Cre) BAC transgene express Cre recombinase under control of the integrin alpha X gene (Itgax or Cd11c) promoter/enhancer regions within the BAC transgene. These Cd11c-Cre transgenic mice are a Cre-lox tool for deletion of floxed sequences in CD8-, CD8+ dendritic cells, tissue-derived dendritic cells from lymph nodes, lung and epidermis, as well as plasmacytoid dendritic cells. This strain may be useful for studying dendritic cell homeostasis and function.
型号:GM-J#018966 -Cryorecovery
应用:These CaMKIIalpha-cre T29-1 transgenic mice have the mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a) promoter driving Cre recombinase expression in the forebrain, specifically to the CA1 pyramidal cell layer in the hippocampus.
型号:GM-J#018965 -Cryorecovery
应用:The FABP4-Cre transgene has a 5.4 kbp mouse Fabp4 promoter directing expression of Cre recombinase. These FABP4-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in brown and white adipose tissue.
型号:GM-J#018964 -Available
应用:The K14-Cre transgene has a human keratin 14 promoter directing expression of Cre recombinase. These K14-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in the ectoderm and its derivatives (including the skin, dental epithelium, and oral ectoderm).
型号:GM-J#018963 -Cryorecovery
应用:These Vil1-cre mice express Cre recombinase in villus and crypt epithelial cells of the small and large intestines and may be useful in studies of intestinal organogenesis. In contrast to Villin-cre transgenic mice from founder line 1000 (Stock No. 021504) that are reported be absent of Cre recombinase activity in gonads, these Villin-cre transgenic mice from founder line 997 are reported to have a very low level (<1%) of cells with Cre recombinase activity in the testes.
型号:GM-J#018961 -Cryorecovery
应用:Alb-cre transgenic mice are useful for deletion of loxP-flanked genes in the liver.