型号：GM-J#018280 -Available

应用：Pdgfra-creERTM transgenic mice can be used to create conditional mutations in oligodendrocyte precursor or NG2+ cells in the adult forebrain and spinal cord. They may have applications in studies related to CNS cell repair and replacement.

型号：GM-J#018147 -Cryorecovery

应用：iCre recombinase expression is evident in interneurons of the brain and in amacrine cells of the inner retina.

型号：GM-J#018142 -Cryorecovery

应用：This Igs1 (intergenic site 1, formerly Ubb) knock-in strain gives constitutive expression of a nuclear localized beta-galactosidase/neomycin resistance protein reporter (NLS-beta-geo) in the absence of cre-mediated recombination. Following cre-mediated recombination, the NLS-beta-geo coding region is excised and Wnt11 is expressed.

型号：GM-J#018141 -Cryorecovery

应用：This Ubb (ubiquitin B) knock-in strain gives constitutive expression of a nuclear localized beta-galactosidase/neomycin resistance protein reporter (NLS-beta-geo) in the absence of cre-mediated recombination. Following cre-mediated recombination, the NLS-beta-geo coding region is excised and Wnt5a is expressed.

型号：GM-J#018140 -Cryorecovery

应用：This Igs1 (intergenic site 1, formerly Ubb) knock-in strain gives constitutive expression of a nuclear localized beta-galactosidase/neomycin resistance protein reporter (NLS-beta-geo) in the absence of cre-mediated recombination. Following cre-mediated recombination, the NLS-beta-geo coding region is excised and GFP-V5 is specifically expressed in mitochondria.

型号：GM-J#018139 -Cryorecovery

应用：This Ubb (ubiquitin B) knock-in strain gives consitutive expression of nuclear-localized beta-galactosidase/neomycin resistance protein reporter (NLS-beta-geo) in the absence of cre-mediated recombination. Following cre-mediated recombination, Vangl2 (vang-like 2 (van gogh, Drosophila)) protein with 3xHA (hemagglutinin) tag is expressed.

型号：GM-J#017981 -Cryorecovery

应用：These mice express cre recombinase under the direction of Hoxb6 and are useful for studying gene function during the early stages of limb development.

型号：GM-J#017968 -Cryorecovery

应用：These VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other similar lines. They may have applications related to the study of hematopoietic stem cell lineages derived from vascular endothelial cells.

型号：GM-J#017955 -Cryorecovery

应用：These transgenic mice allow inducible astroglia-specific expression of human MAOB (monoamine oxidase B) and lacZ (beta-galactosidase). With induction, they exhibit neurodegeneration, decreased locomotor activity, mitochondrial dysfunction, astrogliosis, and microglial activation. This strain may have applications in studies related to the initiation and progression of Parkinson's disease.

型号：GM-J#017948 -Cryorecovery

应用：These transgenic mice express a tamoxifen-inducible cre recombinase from the human KRT18, keratin 18, promoter. When induced, cre activity is observed in Merkel cells of the skin and simple epithelia. They may be useful in lineage tracing.