产品型号：GM-J#018785 -Available Now

产品应用：Mice hemizygous for the BAC LRRK2 (G2019S) transgene express a mutant form of human leucine-rich repeat kinase 2 (LRRK2*G2019S) associated with autosomal dominant, late-onset Parkinson's disease directed by the human LRRK2 promoter/enhancer regions on the BAC transgene. These mice represent an in vivo model for studying the dominant toxic effects of mutant LRRK2*G2019S expression.