型号：GM-J#018960 -Cryorecovery

应用：The RIP-Cre transgene has a 668 bp fragment of the rat insulin II promoter, nuclear-localized Cre recombinase, and a 2.1 kbp fragment from the human growth hormone gene. These RIP-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in pancreatic beta cells.

型号：GM-J#018958 -Cryorecovery

应用：The CD19-Cre knockin/knockout allele has a Cre recombinase gene inserted into the first coding exon of the CD19 antigen gene (Cd19); both abolishing endogenous Cd19 gene function and placing cre expression under the control of the endogenous Cd19 promoter/enhancer elements. Cre recombinase

型号：GM-J#018957 -Cryorecovery

应用：ChAT-IRES-Cre knock-in mice express Cre recombinase in cholinergic neurons, without disrupting endogenous Chat expression. These mice may be useful in neurobiological research of motor function, learning and memory, Alzheimer's disease, and Down syndrome, as well as obesity and diabetes research.

型号：GM-J#018956 -Cryorecovery

应用：The LysMcre knock-in/knockout allele has a nuclear-localized Cre recombinase inserted into the first coding ATG of the lysozyme 2 gene (Lyz2); both abolishing endogenous Lyz2 gene function and placing NLS-Cre expression under the control of the endogenous Lyz2 promoter/enhancer elements. These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.

型号：GM-J#018938 -Cryorecovery

应用：Tac2-Cre knock-in/knockout mice have endogenous gene expression abolished and Cre recombinase expression directed to Tac2-expressing cells by the endogenous promoter/enhancer elements of the tachykinin 2 locus. These mice may be useful to generate conditional mutations for studying gain or loss of function and/or mapping in dorsal root ganglia, the dorsal horn of the spinal cord, and parts of the brain.

型号：GM-J#018937 -Cryorecovery

应用：This strain is useful for permanent labeling of a rare and transient subpopulation of mouse embryonic stem (ES) cells that lack the typical inner cell mass pluripotency markers found in two-cell (2C) embryos but can contribute to the development of both embryonic and extraembryonic tissues.

型号：GM-J#018903 -Cryorecovery

应用：These R26MASTR mice express an eGFPcre fusion protein following FLP-mediated recombination, allowing simultaneous eGFP-labeling and cre-mediated deletion of floxed alleles within the same mutant cells.

型号：GM-J#018899 -Cryorecovery

应用：These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#018898 -Cryorecovery

应用：These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.

型号：GM-J#018896 -Cryorecovery

应用：These Krt6-cre/cerulean transgenic mice express cre recombinase and the cerulean variant of green fluorescent protein (GFP) driven by keratin 6 (Krt6) promoter/enhancer elements. They may be useful for generating conditional mutations for studying craniofacial development.