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  • 型号:GM-J#021458 -Cryorecovery

    应用:The MADM-7TG (Igs5TG) allele has the CMV enhancer/chicken beta-actin core promoter, the N-terminal portion of tdTomato, a beta-globin intronic sequence (containing frt and lox sites), and the C-terminal portion of mut4-EGFP all inserted into the Igs5 locus on chromosome 7 (~2.13 cM; ~0.7 kbp downstream of exon 5 of the Rps9 gene). These MADM-7TG mutants are designed for MADM (mosaic analysis with double markers), and must be crossed to MADM-7GT mice harboring a reciprocal mutation at the same locus (Stock No. 021457). This MADM system allows Cre recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation, mitosis, and imprinting.

    2024-11-09 点击次数:0

    型号:GM-J#021457 -Cryorecovery

    应用:The MADM-7GT (Igs5GT) allele has the CMV enhancer/chicken beta-actin core promoter, the N-terminal portion of mut4-EGFP, a beta-globin intronic sequence (containing frt and lox sites), and the MYC-tagged C-terminal portion of tdTomato all inserted into the Igs5 locus on chromosome 7 (~2.13 cM; ~0.7 kbp downstream of exon 5 of the Rps9 gene). These MADM-7GT mutants are designed for MADM (mosaic analysis with double markers), and must be crossed to MADM-7TG mice harboring a reciprocal mutation at the same locus (Stock No. 021458). This MADM system allows Cre recombinase-induced fluorescent labeling of daughter cells to ascertain lineal relationships and pleiotropic gene function in multicellular organisms. These mice may also be useful in studies of cell differentiation, mitosis, and imprinting.

    2024-11-09 点击次数:0

    型号:GM-J#021429 -Cryorecovery

    应用:In this conditional Gt(ROSA)26Sor (gene trap ROSA 26, Philippe Soriano) knock-in strain, Cre excision of a floxed stop cassette enables expression of GFP that is specifically localized to mitochondria. A C-terminal V5 epitope tag is also fused to GFP.

    2024-11-09 点击次数:0

    型号:GM-J#021428 -Cryorecovery

    应用:Cre excision of a floxed stop sequence enables CMV-directed expression of nuclear localized (nls) tdTomato (tdT) fluorescent protein in this Hprt1 (hypoxanthine guanine phosphoribosyl transferase 1) knock-in line.

    2024-11-09 点击次数:0

    型号:GM-J#021427 -Cryorecovery

    应用:Cre excision of a floxed stop sequence enables CMV-directed expression of nuclear localized (nls) GFP in this Hprt1 (hypoxanthine guanine phosphoribosyl transferase 1) knock-in line.

    2024-11-09 点击次数:0

    型号:GM-J#021423 -Cryorecovery

    应用:These transgenic mice express cre recombinase and the mCherry variant of red fluorescent protein under the control of Dlx2 promoter/enhancer elements. They are suitable for use in applications related to the generation of conditional mutations and the study of craniofacial development.

    2024-11-09 点击次数:0

    型号:GM-J#021329 -Cryorecovery

    应用:Exons 9-11 of Gba1 (glucosidase, beta, acid 1) are flanked by loxP sites in this conditional model, useful in studies of Gaucher disease.

    2024-11-09 点击次数:0

    型号:GM-J#021227 -Cryorecovery

    应用:These Brainbow 3.2 (founder line 7) mice allow labeling of individual neuronal types (including neurons of spinal cord, cortex, hippocampus, cerebellum and retina) with approximately 90 distinguishable color variations in cre recombined cells.

    2024-11-09 点击次数:0

    型号:GM-J#021226 -Cryorecovery

    应用:These Brainbow 3.1 (founder line 18) mice allow labeling of individual neuronal types (including neurons in mid-brain, hind-brain neurons, cortex, cerebellum and retina) with approximately 90 distinguishable color variations in cre recombined cells.

    2024-11-09 点击次数:0

    型号:GM-J#021225 -Cryorecovery

    应用:These Brainbow 3.1 (founder line 3) mice allow labeling of individual neuronal types (including motor neurons, cortical neurons, hippocampal neurons, cerebellar neurons, and cerebellar Purkinje cells) with up to 90 distinguishable color variations in cre recombined cells.

    2024-11-09 点击次数:0
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