型号：GM-J#029855 -Cryorecovery

应用：These Snca floxΔneo ROSA26-stop-lacZ reporter mice carry a floxed allele of the Snca gene and the Gt(ROSA)26Sortm1Sho Cre reporter allele. This strain may be useful for generating mutants in which Cre recombinase efficiency can be monitored for applications related to neurodegenerative synucleinopathies, such as Parkinson's disease and multiple system atrophy.

型号：GM-J#029847 -Cryorecovery

应用：These Ret-EGFP knock-in/knock-out mice express the EGFP reporter under the control of the endogenous promoter and are useful in studies of neural and renal development.

型号：GM-J#029803 -Cryorecovery

应用：This Ki67cre/ERT2 knock-in strain expresses tamoxifen inducible Cre recombinase in actively dividing cells.

型号：GM-J#029789 -Cryorecovery

应用：The H2B-TRAP allele (Translating Ribosome Affinity Purification) has a loxP-flanked STOP preventing transcription of two individual components: H2B/mCherry and EGFP/L10a. When expressed, the H2B/mCherry protein allows nuclei-labeling with mCherry (which enables nuclear isolation by fluorescence-based purification). Furthermore, EGFP/L10a fluorescently tags the translating mRNA polysome complex (which enables isolation of RNAs that are actively engaged by ribosomes). Overall, H2B-TRAP mice are a Cre-inducible tool strain that allows labeling and simultaneous isolation of cell type-specific nuclei and mRNA, and are well-suited for studying epigenomics and transcriptomics from specific cell types within a heterogeneous tissue. Of note, the donating investigator also has available their similar mouse line NuTRAP (Stock No. 029899).

型号：GM-J#029788 -Cryorecovery

应用：These Tyr::CreA transgenic mice have the mouse tyrosinase (Tyr) gene promoter and enhancer driving Cre recombinase expression in melanoblasts and melanocytes. These mice may be useful for Cre-lox studies of the melanocyte lineage, melanocyte development and melanoma cells. The transgene integrated on the X chromosome.

型号：GM-J#029735 -Cryorecovery

应用：The Tg-4EBP1mt transgene has a floxed-GFP-3xSTOP cassette preventing expression of constitutively active, mTORC1-nonresponsive mutant variant of human EIF4EBP1. These mice may be useful for Cre recombinase-inducible studies involving mTOR complex 1 signaling and metabolism.

型号：GM-J#029721 -Available

应用：Fxnflox/null::PV-Cre mice have a Cre-conditional frataxin allele, global knockout frataxin allele and parvalbumin neuron-specific Cre recombinase knockin allele - useful to study Friedreich's Ataxia.

型号：GM-J#029720 -Available

应用：Fxnflox/null::MCK-Cre mice have a Cre-conditional frataxin allele, a global knockout frataxin allele and a cardiac/skeletal muscle-specific Cre recombinase transgene - and are useful in studying Friedreich's Ataxia.

型号：GM-J#029690 -Cryorecovery

应用：Foxg1-IRES-Cre knock-in mice contain a Cre recombinase sequence downstream of the Foxg1 promoter. These mice express FOXG1 in the telencephalon.

型号：GM-J#029684 -Available

应用：Pdgfr-β-CreERT2 transgenic mice express tamoxifen-inducible Cre recombinase under the direction of the murine platelet derived growth factor receptor, beta polypeptide (Pdgfrb) promoter/enhancer regions. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in vascular pericytes.