型号：GM-J#030323 -Available Now

应用：Fos2A-iCreER knock-in (also called Fos2A-iCreERT2 or "TRAP2") was designed to have expression of a tamoxifen-inducible, improved Cre recombinase (icre/ERT2) from the Fos promoter/enhancer elements - without disrupting endogenous Fos expression. Fos2A-iCreER mice are a Cre-lox tool allowing inducible iCre recombination in Fos-expressing cells/tissues (including neurons activated by specific somatosensory, visual and auditory stimuli) or behavioral experiences such as enriched environment, fear conditioning or water deprivation. Immediate early genes (IEGs) are the connection between gene expression and a neuron's electrical/synaptic activity (which defines neuronal response properties).

型号：GM-J#030305 -Cryorecovery

应用：Cre-mediated excision of a floxed STOP enables tissue-specific expression of EGFP-tagged ribosomal protein that enables transcriptional profiling using TRAP technology. Expression of EGFP/RPL10a is driven by Eef1a1, a strong promoter that is widely expressed at high levels in the nervous system and in most tissues.

型号：GM-J#030291 -Cryorecovery

应用：These targeted knock-in/knock-out mutant mice express tamoxifen-inducible cre-ERT2 fusion protein from the mouse Ntrk3/TrkC promoter. Expression occurs in Ntrk3-expressing cells, including subsets of dorsal root ganglia neurons and the spinal cord.

型号：GM-J#030290 -Cryorecovery

应用：These knock-in/knock-out targeted mutant mice express tamoxifen-inducible cre-ERT2 fusion protein from the mouse Rorb promoter in the spinal cord dorsal horn and barrel cortex.

型号：GM-J#030289 -Cryorecovery

应用：These knock-in/knock-out targeted mutant mice express tamoxifen-inducible cre-ERT2 fusion protein from the mouse Prkcg promoter in the spinal cord dorsal horn, hippocampus, cerebellum, and corticospinal tract.

型号：GM-J#030277 -Cryorecovery

应用：LSL-Mist1myc transgenic mice express myc-tagged Bhlha15 after exposure to Cre recombinase. Mice are useful when studying pancreatic acinar cell damage and repair during acute pancreatitis.

型号：GM-J#030220 -Cryorecovery

应用：Ai140(TIT2L-GFP-ICL-tTA2)-D (also called Ai140D) mice are a Cre-dependent, Tet-controllable fluorescent reporter line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Exposure to Cre recombinase removes both STOP cassettes - resulting in EGFP fluorescence and tTA2 expression - and that EGFP expression may be diminished/eliminated by doxycycline.

型号：GM-J#030219 -Cryorecovery

应用：Ai139(TIT2L-GFP-ICL-TPT)-D (also called Ai139D) mice are a Cre-dependent, Tet-controllable dual fluorescent reporter line, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Exposure to Cre recombinase removes both STOP cassettes - resulting in EGFP fluorescence, tdTomato fluorescence and tTA2 expression - and that EGFP expression may be diminished/eliminated by doxycycline.

型号：GM-J#030218 -Available

应用：Fxnnull::PV-Cre mice harbor a frataxin global knockout allele and a Pvalb knock-in allele directing Cre recombinase expression to parvalbumin-expressing neurons. These mice are a parental control used to generate the progressive ataxia mouse line Fxnflox/null::PV-Cre (Stock No. 029721), and may be useful in studying Friedreich's Ataxia.

型号：GM-J#030217 -Cryorecovery

应用：TITL-R-CaMP1.07-D (Ai143D) mice are a Cre/Tet-dependent, fluorescent calcium-indicator tool strain, created by targeted insertion at the Igs7 locus (TIGRE; an intergenic region on mouse chromosome 9 that allows reporter expression to be tightly regulated). Following Cre-mediated removal of the STOP cassette, they may be used to generate Tet-Off/Tet-On mutant animals with conditional (inducible/reversible) expression of R-CaMP1.07 (a red fluorescent calcium-sensing molecule that functions at cellular calcium levels).