型号：GM-J#029485 -Cryorecovery

应用：These Gsx1cre transgenic mice express Cre recombinase under the control of the Gsx1 promoter and may be useful for generating conditional mutations for studying gain/loss of function or fate mapping in Gsx1 expressing neurons.

型号：GM-J#029481 -Not Available At Jax

应用：This strain is extinct. Please search the JAX® Mice Database for similar inducible tissue-specific cre strains.

型号：GM-J#029428 -Cryorecovery

应用：The Cdh6CreER (Cdh6-CreER) knock-in/knock-out allele was designed to both abolish endogenous gene function and allow the Cdh6 promoter/enhancer regions to direct tamoxifen-inducible Cre recombinase expression to ON-OFF direction-selective retinal ganglion cells (ooDSGCs) that respond to vertical motion (dorsal and ventral), as well as to starburst amacrine cells. These mice may be useful for tamoxifen-inducible recombination of lox-flanked (floxed) alleles in studying photoreceptors and retinal circuitry.

型号：GM-J#029417 -Cryorecovery

应用：The JAM-B-CreER transgene has the junction adhesion molecule 2 promoter/enhancer regions directing tamoxifen-inducible Cre recombinase expression to OFF direction-selective retinal ganglion cells that respond to upward/dorsal motion (J-RGCs). These mice may be useful for tamoxifen-inducible recombination of lox-flanked (floxed) alleles in studying photoreceptors and retinal circuitry.

型号：GM-J#029416 -Cryorecovery

应用：The Neto1Cre knock-in/knock-out allele was designed to both abolish endogenous gene function and allow the Neto1 promoter/enhancer regions to direct Cre recombinase expression to type 2 OFF bipolar cells (BC2s), as well as some amacrine cells and retinal ganglion cells (RGCs). These mice may be useful for recombining lox-flanked (floxed) alleles in studying photoreceptors and retinal circuitry.

型号：GM-J#029414 -Cryorecovery

应用：The Kcng4Cre knock-in/knock-out allele was designed to both abolish endogenous gene function and allow the Kcng4 promoter/enhancer regions to direct Cre recombinase expression to type 5 ON bipolar cells (BC5s), as well as subsets of alpha retinal ganglion cells (a-RGC). These mice may be useful for recombining lox-flanked (floxed) alleles in studying photoreceptors and retinal circuitry.

型号：GM-J#029412 -Cryorecovery

应用：These mb1-cre knock-in/knock-out mice carry an allele in which exons 2 and 3 of the Cd79a gene have been replaced with a codon optimized Cre recombinase gene and the ATG codon of exon 1 is deleted; both abolishing endogenous Cd79a gene function and placing cre expression under the control of the endogenous Cd79a promoter/enhancer elements. Cre recombinase expression is directed at the earliest stages and throughout B-lymphocyte development and differentiation. Homozygous mice are also useful for studying B cell-deficiency.

型号：GM-J#029394 -Cryorecovery

应用：Rosa26-ATF4loxtg mutant mice carry a floxed stop/FLAG-tagged human ATF4 cassette knocked into the mouse Gt(ROSA)26Sor gene. Cre-mediate excision of the floxed stop enables site-directed expression of FLAG-tagged human ATF4 protein.

型号：GM-J#029317 -Cryorecovery

应用：These CRISPR/Cas9 generated mice carry the Park2, Parkinson disease (autosomal recessive, juvenile) 2, parkin, W402A point mutation in exon 11. These mice may be useful in studies of Parkinson's disease and other neurobiological research.

型号：GM-J#029312 -Cryorecovery

应用：Bmp7-CreERT2 KI/KO mice may be useful for applications requiring tamoxifen-induced deletion of floxed sequences during cloacal septation and sexual differentiation of the genital tubercle.