型号：GM-J#031330 -Cryorecovery

应用：These 6ax:pVBI347-L2 compound mutant mice carry a targeted knock-out allele of the endogenous mouse Gdf6 gene in addition to a 3' GDF6 enhancer transgene derived from chimpanzee (lacking in humans) driving expression of tamoxifen-inducible cre recombinase (cre/ERT2).

型号：GM-J#031327 -Cryorecovery

应用：Gdf5-Cre transgenic mice express cre recombinase from the mouse Gdf5 promoter in developing joints, including early joint interzones, adult articular cartilage, and the joint capsule. These mice are useful in studies of articular cartilage and arthritis.

型号：GM-J#031303 -Available

应用：Oxtr-T2A-Cre-D knock-in mice are designed to have Cre recombinase expression/activity directed by the endogenous oxytocin receptor promoter/enhancer sequences. In the brain, it is observed in restricted populations within the hippocampal formation, cortical subplate, striatum, thalamus, hypothalamus and medulla. Sparse, scattered expression is present in the cortex. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in OXTR-expressing cells.

型号：GM-J#031302 -Cryorecovery

应用：iChr2-Control-Mosaic mice allow three possible Cre recombination outcomes in any single cell. Each outcome results in expression of a chromatin/nuclear-targeted fluorescent protein, and each is mutually exclusive and permanent. These mice are also designed to permit further introduction of genes of interest for inducible, fluorescent and functional genetic mosaic analysis (ifgMosaic).

型号：GM-J#031301 -Cryorecovery

应用：iMb2-Control-Mosaic mice allow three possible Cre recombination outcomes in any single cell. Each outcome results in expression of a membrane-bound fluorescent protein, and each is mutually exclusive and permanent. These mice are also designed to permit further introduction of genes of interest for inducible, fluorescent and functional genetic mosaic analysis (ifgMosaic).

型号：GM-J#031298 -Cryorecovery

应用：iMb2-Control-Mosaic::iChr2-Control-Mosaic compound heterozygous mice allow several possible Cre recombination outcomes in any single cell. Each outcome results in expression of both a membrane-bound fluorescent protein and a chromatin/nuclear-localized fluorescent protein, and each is mutually exclusive and permanent. These mice are also designed to permit further introduction of genes of interest for inducible, fluorescent and functional genetic mosaic analysis (ifgMosaic or Dual ifgMosaic).

型号：GM-J#031289 -Cryorecovery

应用：Lmx1b-IREScreERT2 mice have an IREScreERT2 fusion protein inserted into the 3’ UTR of the LIM homeobox transcription factor 1 beta gene. Mice are useful for studying musculoskeletal patterning during mouse limb development.

型号：GM-J#031286 -Cryorecovery

应用：MrgprdCreERT2 mice express tamoxifen-inducible Cre recombinase under the direction of the MAS-related GPR, member D promoter in non-peptidergic dorsal root ganglion and trigeminal ganglion neurons. These mice are useful for systematic sparse genetic tracing of non-peptidergic nociceptors that mediate mechanical pain and beta-alanine triggered itch.

型号：GM-J#031281 -Cryorecovery

应用：Tyr::CreERT2 mice have expression of CreERT2 fusion protein directed by mouse tyrosinase promoter/enhancer regions. When bred with mice containing loxP-flanked sequences, tamoxifen/4-hydroxytamoxifen-inducible Cre-mediated recombination will result in deletion of the floxed sequences in the Tyr-expressing cells of the offspring. These mice are a Cre-lox tool that allows inducible Cre expression in melanoblasts and melanocytes.

型号：GM-J#031121 -Cryorecovery

应用：These VEGF-luciferase mice express firefly luciferase under direction of the Vegfa (vascular endothelial growth factor A) promoter. Mice are associated with organ-specific gene expression responses to hypoxic stress.