型号：GM-J#034391 -Cryorecovery

应用：Celf4-iCreER mice have a CRISPR/Cas9-generated Celf4-3xHA-P2A-iCreER-T2A-EGFP cassette inserted immediately before the stop codon of the CUGBP, Elav-like family member 4 (Celf4) gene. These mice are useful for visualizing inner ear cochlear spiral ganglion neurons (SGNs) and as a tool for studying SGN developmental and regenerative studies.

型号：GM-J#034382 -Cryorecovery

应用：K13CRE mice express cre recombinase from the mouse Krt13 (keratin 13) promoter in superficial oral, esophageal and urogenital epithelium. Expression is not seen in skin.

型号：GM-J#034320 -Available

应用：This strain serves as a Cre reporter strain. When used in conjunction with a Cre recombinase-expressing strain, successful Cre-mediated excision is indicated by luciferase expression in Cre-expressing tissues.

型号：GM-J#034304 -Cryorecovery

应用：Gpr139-IRES2-FlpO-WPRE knock-in mice are designed to have optimized FLP recombinase expression directed to G protein-coupled receptor 139-expressing cells. FlpO expression/activity is observed in many locations throughout brain, with especially strong expression in olfactory bulb, striatum, lateral septum, hippocampus, amygdala, hypothalamus, midbrain, and strong scattered expression in layer 6 of cortex with less frequent scattered expression in other layers. These mice may be used to generate conditional mutations for studying GPR139 function in motor control, locomotor activity, metabolism, dopaminergic mesolimbic pathways, addiction, Parkinson's disease and schizophrenia.

型号：GM-J#034302 -Cryorecovery

应用：Chrna6-IRES2-FlpO-WPRE-neo knock-in mice are designed to have optimized FLP recombinase expression directed to CHRNA6-expressing cells. FlpO expression/activity is observed in many locations throughout brain, including striatum, lateral geniculate nucleus, superior colliculus, Layer 5 of cortex, medulla, and cerebellum. These mice may be used to generate conditional mutations for studying α6-containing nicotinic acetylcholine receptors, for example, the role of dopaminergic neurons in nicotine addiction or as a possible therapeutic target for Parkinson's disease treatment.

型号：GM-J#034278 -Cryorecovery

应用：Pnoc-IRES-Cre knock-in mice express a Cre recombinase gene inserted upstream of the stop codon of the prepronociceptin (Pnoc) gene. These mice can be used to identify Pnoc expressing cell populations or study pain sensitivity and reward behavior.

型号：GM-J#034261 -Cryorecovery

应用：Ighg3T2A-Cre knock-in mice express Cre recombinase under the direction of the Ighg3 promoter in B-1a cells.

型号：GM-J#034244 -Cryorecovery

应用：HKCreERT2 transgenic mice express a tamoxifen-inducible Cre recombinase directed by mouse Atp4a promoter elements. When induced, Cre recombinase activity is observed in gastric parietal cell.

型号：GM-J#034240 -Cryorecovery

应用：R26-CAG-lsl-CaMPARI2 mice express CaMPARI2 fluorescent calcium reporter from a CAG promoter introduced to the Gt(ROSA)26Sor gene when a loxP-flanked STOP cassette is excised with Cre recombinase. CaMPARI changes from green to red fluorescence with high intracellular calcium and photoconversion light, and is thus useful in monitoring neuronal activity. A poster describing the strain can be found here.

型号：GM-J#034186 -Cryorecovery

应用：Ins1cre knockin/knockout mice express Cre recombinase in insulin-producing beta cells of pancreas starting at birth.