型号：GM-J#033999 -Cryorecovery

应用：Adcyap1-2A-CreER knock-in mice express tamoxifen-inducible CreERT2 fusion protein from the mouse Adcyap1 (adenylate cyclase activating polypeptide 1) promoter in ADCYAP1-positive neurons of the neocortex and pons.

型号：GM-J#033984 -Cryorecovery

应用：These β-actin-cre transgenic mice express Cre recombinase directed by the human beta actin gene promoter. Cre recombinase activity is widespread in the embryo by the blastocyst stage of development.

型号：GM-J#033969 -Cryorecovery

应用：Rln3-Cre mice (also called Rln3-IRES-Cre/GFP) are designed to have the endogenous relaxin 3 promoter/enhancer driving Cre/GFP fusion protein expression to nucleus incertus (NI) of the pontine tegmentum (a subset of NI GABAergic neurons) and to smaller populations of Rln3-expressing neurons found in the periaqueductal gray and adjacent to the substantia nigra. While Rln3-Cre was designed to retain endogenous Rln3 expression, this allele is hypomorphic; as such it is recommended that Rln3-Cre heterozygotes be used for Cre-lox applications. These mice may be used to generate conditional mutations in RLN3+ cells for studying physiological processes such as stress, memory and appetite regulation, as well as neuropeptide signaling processes.

型号：GM-J#033951 -Available

应用：Dbhcre knock-in/knock-out mice express Cre recombinase from the endogenous Dbh locus, abolishing endogenous Dbh gene expression. Cre recombinase activity is detected in noradrenergic neurons.

型号：GM-J#033944 -Cryorecovery

应用：Bdnf-e6-/- mice have an EGFP-STOP cassette inserted upstream of the splice donor site of exon 6 of the brain derived neurotrophic factor (Bdnf) gene. These mice may be useful when studying the functional role of BDNF production from unique promoters in aggression and serotonin signaling.

型号：GM-J#033943 -Cryorecovery

应用：Bdnf-e4-/- mice have an EGFP-STOP cassette inserted upstream of the splice donor site of exon 4 of the brain derived neurotrophic factor (Bdnf) gene. These mice may be useful when studying the functional role of BDNF production from unique promoters in aggression and serotonin signaling.

型号：GM-J#033942 -Cryorecovery

应用：Bdnf-e2-/- mice have an EGFP-STOP cassette inserted upstream of the splice donor site of exon 2 of the brain derived neurotrophic factor (Bdnf) gene. These mice may be useful when studying the functional role of BDNF production from unique promoters in aggression and serotonin signaling.

型号：GM-J#033941 -Cryorecovery

应用：Bdnf-e1-/- mice have an EGFP-STOP cassette inserted upstream of the splice donor site of exon 1 of the brain derived neurotrophic factor (Bdnf) gene. These mice may be useful when studying the functional role of BDNF production from unique promoters in aggression and serotonin signaling.

型号：GM-J#033897 -Cryorecovery

应用：AID-Cre-ERT2 knock-in/knock-out mice have an inducible Cre/ERT2 fusion gene inserted into exon 2 of the activation-induced cytidine deaminase (Aicda or AID) gene. When combined with a floxed reporter, these mice can be used to monitor memory B cell populations.

型号：GM-J#033895 -Cryorecovery

应用：Egr1-Cre-ERT2; Snap25-Flpe (ECSF) bi-transgenic BAC mice were originally designed to enable selective genetic targeting of non-myelinated Remak Schwann cells. Mice carry both a tamoxifen-inducible/FRT-flanked Cre recombinase driven by the mouse Egr1 promoter (expressed in Remak Schwann cells and some neurons), and Flpe recombinase driven by the Snap25 promoter (associated with pan-neuronal expression).