型号：GM-J#035435 -Available

应用：Xcr1Cre knock-in mice express an mCherry fluorescent protein and an icre recombinase sequence under the direction of the Xcr1 promoter in conventional type 1 dendritic cells (cDC1).

型号：GM-J#035412 -Available

应用：Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

型号：GM-J#035404 -Cryorecovery

应用：TIGRE-MORF(Ai166) is one of a set of a Cre reporter tool strains (also including MORF1 and MORF3) that use mononucleotide repeat frameshift (MORF) as a translation switch for cell labeling in vivo. TIGER-MORF (Ai166) mice express a cre-dependent tetracycline-activated EGFP fluorescent protein that is proceeded by a polyguanine repeat (G22) MORF switch. Exposure to Cre recombinase removes both STOP cassettes unblocking EGFP fluorescence and tTA2 expression and in the presence of spontaneous frameshift the EGFP reporter provides sparse and stochastic labeling of neural cells. In addition, reporter expression may be diminished/eliminated by doxycycline. TIGER-MORF(Ai166) can be used for high level direct fluorescent sparse labeling of Cre+ neuronal and glial cells.

型号：GM-J#035401 -Available

应用：LysoTag (Rosa26; lox-stop-lox-Tmem192-3xHA) mice conditionally express human TMEM192 cDNA fused to a hemagglutinin (3xHA) tag upon Cre recombinase-mediated excision of a loxP-flanked STOP cassette. Expression of the HA tag enables rapid, tissue-specific, anti-HA antibody-driven immunoisolation of intact lysosomes for content profiling.

型号：GM-J#035400 -Cryorecovery

应用：MORF1 is one of a set of a Cre reporter tool strains (also including MORF3 and TIGRE-MORF) that use mononucleotide repeat frameshift (MORF) as a translation switch for cell labeling in vivo. MORF1 mice express a cre-dependent mNeonGreen fluorescent protein that is proceeded by a polycytosine repeat (C22) MORF switch under the control of a CAG promoter. Cre recombination combined with a spontaneous frameshift results in sparse and stochastic labeling of neural cells.

型号：GM-J#035272 -Cryorecovery

应用：Pitx1/Cre transgenic mice express cre recombinase under the control of the mouse Pitx1 (paired-like homeodomain transcription factor 1) promoter. Cre is expressed in the craniofacial and oral ectoderm as early as E9.5 before the formation of Rathke's pouch, so it is useful for targeting the nascent anterior pituitary gland before the specification of hormone producing cell types.

型号：GM-J#035271 -Cryorecovery

应用：Prop1-Cre mice express cre recombinase from the mouse Prop1 (paired like homeodomain factor 1) gene. Expression of the transgene is found in Rathke's pouch during pituitary organogenesis and in olfactory epithelium beginning at embryonic day 11.5 (E11.5) and declining after birth.

型号：GM-J#035233 -Cryorecovery

应用：MLR10 transgenic mice exhibit cre recombinase expression in both the lens epithelium and lens fibers under the transcriptional control of the mouse Cryaa (crystallin, alpha A) promoter modified by the insertion of a Pax6 consensus binding element/lens epithelial cell enhancer. Cre expression is not found in other parts of the eye.

型号：GM-J#035229 -Available

应用：CRISPR/Cas9 generated CCR2-CreER-GFP mice express cre-ERT2 and EGFP directed from the endogenous chemokine (C-C motif) receptor 2 (Ccr2) promoter. They are useful for applications requiring tamoxifen-induced deletion of floxed sequences in monocytes.

型号：GM-J#035208 -Cryorecovery

应用：hMPO (MPOG) transgenic mice express the intact human myeloperoxidase (MPO) gene bearing a -463G promoter polymorphism, along with introns and flanking regions. This strain is useful in studies of human MPO involvement in models of inflammatory and neurodegenerative diseases, as well as cancer.