型号：GM-J#035703 -Cryorecovery

应用：Igfbp2-CreERT2 knock-in mice have the endogenous insulin-like growth factor binding protein 2 promoter/enhancer sequences directing expression of tamoxifen-inducible Cre recombinase. These mice are a Cre-lox tool allowing inducible Cre recombination in Igfbp2-expressing cells/tissues (including pulmonary AT1 cells), and may be useful in studying developmental biology and lung cell differentiation and regeneration.

型号：GM-J#035702 -Cryorecovery

应用：ErGFPcre knock-in/knock-out mice have an EGFP reporter fused to an iCre recombinase cDNA inserted into the 5’ UTR of the erythropoietin receptor (Epor) gene. EGFP/iCre is expressed by erythroid progenitors. This strain may be useful as a reporter for lineage tracing and a Cre-lox tool for deletion of floxed sequences in cells in the erythroid lineage.

型号：GM-J#035699 -Cryorecovery

应用：LoxP-STOP-loxP-SAA3 (also called LSL-SAA3) knock-in mice carry a conditional mutant allele in which Saa3 (serum amyloid A 3) and IRES-EGFP are over-expressed from a CAG promoter upon Cre recombinase-mediated excision of a loxP-flanked neomycin/Stop cassette. EGFP expression has not been assessed. This strain has been useful in studies of Th17 cell responses, inflammation, and autoimmunity.

型号：GM-J#035695 -Cryorecovery

应用：LoxP-STOP-loxP-SAA1 (also called LSL-SAA1) knock-in mice carry a conditional mutant allele in which Saa1 (serum amyloid A 1) and IRES-EGFP are over-expressed from a CAG promoter upon cre recombinase-mediated excision of a loxP-flanked neomycin/Stop cassette. This strain has been useful in studies of Th17 cell responses, inflammation, and autoimmunity. The functionality of the EGFP reporter has not been assessed.

型号：GM-J#035687 -Cryorecovery

应用：H2B::PaGFP mice carry a photoactivatable histone H2B/green fluorescent protein fusion gene (Pa-GFP) behind a floxed STOP cassette (LSL). In the presence of Cre recombinase and photoactivation, bright nuclear fluorescence can be detected, allowing for the observation and measurement of nuclear and chromatin dynamics in vivo.

型号：GM-J#035670 -Available

应用：Vav-Cre transgenic mice express Cre recombinase under the control of the human vav 1 oncogene (VAV1) regulatory elements in all nucleated blood cells as well as hematopoietic stem cells. This strain may be useful as a Cre-lox tool for deletion of floxed sequences in cells of the hematopoietic system.

型号：GM-J#035668 -Cryorecovery

应用：These GATA1-cre transgenic mice express Cre recombinase in most tissues under the control of the mouse GATA binding protein 1 (Gata1) promoter beginning at E10.5. This strain may be useful for generating conditional deletions in developing embryos and in multiple adult tissues. This strain also is available on the 129S background (Stock No. 035667).

型号：GM-J#035667 -Cryorecovery

应用：These GATA1-cre transgenic mice express Cre recombinase in most tissues under the control of the mouse GATA binding protein 1 (Gata1) promoter beginning at E10.5. This strain may be useful for generating conditional deletions in developing embryos and in multiple adult tissues. This strain also is available on the C57BL/6J background (Stock No. 035668).

型号：GM-J#035595 -Cryorecovery

应用：Mice harboring the vil-Cre transgene have the 9-kb mouse, Vil1, villin 1, promoter directing expression of Cre recombinase to the intestinal epithelia and kidney, and may be useful for generating conditional mutations in cells of the crypt–villus axis and kidney. This strain also is available on the C57BL/6N background (Stock No. 033019).

型号：GM-J#035593 -Cryorecovery

应用：Alb-cre transgenic mice express cre recombinase under the control of the mouse albumin enhancer/promoter. This strain may be useful for generating conditional deletions in heptaocytes. This strain also is available on the C57BL/6 background (Stock No. 003574).