型号：GM-J#035576 -Cryorecovery

应用：Tacr3iCre:GFP knock-in mice should express iCre:GFP wherever Tacr3 (tachykinin receptor 3), a G protein-coupled receptor (GPCR), is normally expressed. Mice demonstrate no overt phenotype. Expression levels of the targeted gene have not been assessed, but no effect is anticipated as the insertion is beyond the termination codon.

型号：GM-J#035575 -Cryorecovery

应用：Ptger3Cre:GFP knock-in mice express Cre:GFP wherever Ptger3 (prostaglandin E receptor 3 (subtype EP3)), a G protein-coupled receptor (GPCR), is normally expressed. Heterozygotes demonstrate no overt phenotype. The initiation codon and first 40 amino acids of the protein are deleted, no functional receptor is likely expressed by the targeted allele, but this has not been confirmed. These mice allow cre recombinase-dependent expression of effector/reporter genes in cells that normally express this receptor.

型号：GM-J#035574 -Cryorecovery

应用：Oprm1Cre:GFP knock-in/knock-out mice express Cre:GFP wherever Oprm1 (opioid receptor, mu 1), a G protein-coupled receptor (GPCR), is normally expressed. Heterozygotes demonstrate no overt phenotype. Homozygotes lack mu opioid receptor expression and hence no longer respond to certain endogenous or exogenous ligands. These mice allow cre recombinase-dependent expression of effector/reporter genes in cells that normally express this receptor.

型号：GM-J#035573 -Cryorecovery

应用：Avpr1a1iCre:GFP knock-in mice should express iCre:GFP wherever Avpr1a (arginine vasopressin receptor 1A), a G protein-coupled receptor (GPCR), is normally expressed. Expression levels of the targeted gene have not been assessed, but no effect is anticipated as the insertion is beyond the termination codon.

型号：GM-J#035572 -Cryorecovery

应用：Adcyap1r1iCre:GFP knock-in mice should express iCre:GFP wherever Adcyap1r1 (adenylate cyclase activating polypeptide 1 receptor 1), a G protein-coupled receptor (GPCR), is normally expressed. Expression levels of the targeted gene have not been assessed, but no effect is anticipated as the insertion is beyond the termination codon.

型号：GM-J#035554 -Cryorecovery

应用：Lfng-CreERT2 transgenic mice have a cre/ERT2 fusion gene under direction of the mouse LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Lfng, also known as Lunatic fringe) promoter/enhancer sequences. These mice retain normal endogenous Lfng expression and have tamoxifen-inducible Cre expressed in neural stem cells of the hippocampus.

型号：GM-J#035552 -Cryorecovery

应用：Tecta-Cre knock-in/knock-out mice express Cre recombinase under direction of the tectorin alpha (Tecta) promoter in the sensory epithelium in the cochlea. Homozygous mice are deaf, while heterozygous mice are not. These mice are useful when studying congenital deafness.

型号：GM-J#035549 -Cryorecovery

应用：Color-Switch PER2::LUC reporter mice switch from click beetle red PER2 (period circadian clock 2)::LUCIFERASE protein expression to click beetle green PER2::LUCIFERASE expression upon cre recombination. This enables cell-type-specific circadian measurements.

型号：GM-J#035547 -Cryorecovery

应用：Mmp3 null mice carry a CRISPR/Cas9 generated 1 bp deletion in the catalytic domain of the matrix metallopeptidase 3 (Mmp3), resulting in a premature stop codon, making this strain useful when studying protective responses at the level of the neurovascular unit upon central nervous system injury.

型号：GM-J#035452 -Cryorecovery

应用：Uts2bCre (Uts2b2A-Cre) mice express a CRISPR/Cas9-generated T2A-cre recombinase knock-in from the mouse Uts2b (urotensin 2B) promoter. Reporters indicate that cre expression patterns are identical to those of the endogenous Uts2b gene based on in situ hybridization (ISH) results available through the Allen Brain Institute. This strain has been useful in the mapping of vagal sensory neurons in the intestine.