型号：GM-J#038840 -Available For Pre-Order

应用：Sdk2ce/ce knock-in/knock-out mice have a cre/ERT2 fusion gene replacing exons 1-2, including the ATG start site, of the Sdk2 gene. This strain is useful for studying interneurons and retinal ganglion cell synapses and their role in visual function.

型号：GM-J#038835 -Available For Pre-Order

应用：CRISPR/Cas9 generated Sdk1::CreGFP knock-in/knock-out mice have a cre/GFP fusion gene inserted at the translation start site of the Sdk1 gene. This strain is useful for studying interneurons and retinal ganglion cell synapses and their role in visual function.

型号：GM-J#038834 -Available For Pre-Order

应用：Sdk1ce/ce knock-in/knock-out mice have a cre/ERT2 fusion gene replacing exons 1-2, including the ATG start site, of the Sdk1 gene. This strain is useful for studying interneurons and retinal ganglion cell synapses and their role in visual function.

型号：GM-J#038831 -Available For Pre-Order

应用：Efnb2-CreERT2 knock-in mice carry an inducible Cre recombinase-ERT2 fusion protein inserted into the Efnb2 (ephrin B2) locus. Mice have inducible cre expression in the arteries. This strain may be useful for arterial lineage tracing of hematopoietic stem cells.

型号：GM-J#038824 -Available For Pre-Order

应用：Myh11-CreERT2-P2A knock-in mice carry an inducible Cre recombinase-ERT2 fusion protein inserted into the Myh11 (myosin, heavy polypeptide 11, smooth muscle) locus. Mice have inducible cre expression in smooth muscle cells with minimal impact on endogenous Myh11 expression. This strain may be useful for research involving smooth muscle cells and smooth muscle cell-dependent cardiovascular diseases.

型号：GM-J#038823 -Available For Pre-Order

应用：Myh11-CreNLSP2A knock-in mice carry a codon optimized Cre recombinase (icre) fused to ERT2 inserted into the Myh11 (myosin, heavy polypeptide 11, smooth muscle) locus. Please note: tamoxifen administration does not further augment Cre activity, necessitating its use as a constitutive Cre model.  Mice have constitutive cre expression in smooth muscle cells without disrupting endogenous Myh11 expression. This strain may be useful for research involving smooth muscle cells and smooth muscle cell-dependent cardiovascular diseases.

型号：GM-J#038799 -Available For Pre-Order

应用：3RTau (Line 13) transgenic mice carry the mouse Thy1 promoter driving expression of human MAPT containing three ~32 amino acid repeats bearing the L266V and G272V mutations. These mice may be useful in studying neurodegenerative tauopathies, such as familial Pick's disease.

型号：GM-J#038796 -Available For Pre-Order

应用：Line 61 (mThy-1 hα-synuclein) transgenic mice express wildtype human α-synuclein cDNA driven by the mouse thymus cell antigen 1, theta (Thy1) promoter. These mice may be useful in studying human neuronal α-synucleinopathies, such as familial Parkinson's disease.

型号：GM-J#038775 -Available

应用：D Line (PDGFβ-hαsyn) transgenic mice express wildtype human α-synuclein cDNA driven by the platelet derived growth factor, B polypeptide (PDGFB) promoter. These mice may be useful in studying human neuronal α-synucleinopathies, such as familial Parkinson's disease.

型号：GM-J#038774 -Available For Pre-Order

应用：PDGFβ-hαsyn-eGFP transgenic mice have the human platelet-derived growth factor-β (PDGFB) promoter directing expression of the human α-synuclein (SNCA) gene fused to an enhanced green fluorescent protein (eGFP) in various neuronal cell types. These mice may be useful for visualizing the accumulation of α-synuclein in neuronal cell bodies in α-synucleinopathies, such as familial Parkinson's disease.