型号：GM-J#038954 -Cryorecovery

应用：Vipr2-IRES2-Cre-neo knock-in mice are designed to have Cre recombinase expression/activity directed by the endogenous vasoactive intestinal peptide receptor 2 promoter/enhancer sequences. In the brain, it is observed in arcuate hypothalamic nucleus, dorsal lateral geniculate nucleus, ventral nucleus of the thalamus and bed nuclei of the stria terminalis, with scattered expression in superior colliculus and throughout the cortex. These mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping in VIPR2-expressing cells.

型号：GM-J#038953 -Available For Pre-Order

应用：Chrna6-IRES2-FlpO-neo knock-in mice are designed to have optimized FLP recombinase expression directed to CHRNA6-expressing cells. FlpO expression/activity is observed in many locations throughout brain, with sparse labeling in Layer 5ET and none in Layer 6b. These mice may be used to generate conditional mutations for studying α6-containing nicotinic acetylcholine receptors, for example, the role of dopaminergic neurons in nicotine addiction or as a possible therapeutic target for Parkinson's disease treatment.

型号：GM-J#038896 -Available For Pre-Order

应用：MBP hα-syn Line 29 transgenic mice express wildtype human α-synuclein cDNA driven by the mouse Mbp promoter. These mice may be useful in studying human neuronal α-synucleinopathies, such as multiple systems atrophy (MSA).

型号：GM-J#038895 -Available For Pre-Order

应用：MBP hα-syn Line 1 transgenic mice express wildtype human α-synuclein cDNA driven by the mouse Mbp promoter. These mice may be useful in studying human neuronal α-synucleinopathies, such as multiple systems atrophy (MSA).

型号：GM-J#038892 -Available For Pre-Order

应用：CAG-LSL-KZ-Fluc2 mice harbor the Fluc2 conditional allele, a codon-optimized firefly luciferase that with its' substrate, D-luciferin2, provides a light emission peak around 590 nm and a light output stronger than that generated by firefly luciferase. This strain may be useful for inducible tissue specific bioluminescence imaging and bioluminescent resonance energy transfer (BRET).

型号：GM-J#038891 -Available For Pre-Order

应用：CAG-LSL-CaMBI-110 mice harbor the CamBI 110 conditional allele, Antares-derived, orange-emitting, calcium-modulated bioluminescent indicator that with its' substrate, hydrofurimazine provides improved solubility and higher brightness. This strain may be useful for inducible tissue specific bioluminescence imaging and bioluminescent resonance energy transfer (BRET).

型号：GM-J#038890 -Available For Pre-Order

应用：CAG-LSL-CaMBI-300mice harbor the CamBI 300 conditional allele, Antares-derived, orange-emitting, calcium-modulated bioluminescent indicator that with its' substrate, hydrofurimazine provides improved solubility and higher brightness. This strain may be useful for inducible tissue specific bioluminescence imaging and bioluminescent resonance energy transfer (BRET).

型号：GM-J#038889 -Available For Pre-Order

应用：CAG-LSL-KZ-CyOFP1-NanoLuc-CyOFP1 mice harbor the Antares conditional allele, a highly catalytic blue-emitting modified firefly luciferase (NanoLuc), fused to two copies of the cyan excitable fluorescent protein, CyOFP1, that with its' substrates, hydrofurimazine, cephalofurimazine, and fluorofurimazine provide improved solubility and higher brightness. This strain may be useful for inducible tissue specific bioluminescence imaging and bioluminescent resonance energy transfer (BRET).

型号：GM-J#038888 -Available For Pre-Order

应用：CAG-LSL-KZ-Akaluc mice harbor the Akaluc conditional allele, a modified firefly luciferase that with its' substrate, the luciferin analogue, Akalumine-HCl, provides a light emission peak around 650 nm (near infrared emission) and a light output stronger than that generated by firefly luciferase. This strain may be useful for inducible tissue specific bioluminescence imaging and bioluminescent resonance energy transfer (BRET).

型号：GM-J#038840 -Available For Pre-Order

应用：Sdk2ce/ce knock-in/knock-out mice have a cre/ERT2 fusion gene replacing exons 1-2, including the ATG start site, of the Sdk2 gene. This strain is useful for studying interneurons and retinal ganglion cell synapses and their role in visual function.