型号:GM-J#004178 -Cryorecovery
应用:When bred to a strain expressing Cre recombinase, enhanced GFP replaces lacZ in tissues expressing Cre in this double reporter system. Expression is widespread and observed in embryonic and adult stages except in liver and lung tissue.
型号:GM-J#004146 -Available
应用:These transgenic mice express a cre gene inserted into exon 4 of a Pcp2 gene. Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons and is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth.
型号:GM-J#004128 -Available
应用:Cre recombinase expression is driven by a mouse endothelial-specific receptor tyrosine kinase promoter/enhancer. Recombinase activity is detected in endothelial cells during embryogenesis and adulthood. Expression was also detected in hematopoietic cells and germline.
型号:GM-J#004126 -Cryorecovery
应用:Homozygous mice are Cd19-deficient, whereas heterozygous mice are phenotypically normal and can be used for specific deletion of floxed targets in B-lymphocytes. Homozygous mice are severely impaired in their ability to respond to T-cell-dependent antigens and fail to form splenic germinal centers. A deficiency in the B-1 subset of B-lymphocytes is observed along with a concomitant reduction in serum IgM.
型号:GM-J#004077 -Available
应用:These mice contain an Enhanced Green Fluorescent Protein (EGFP) gene inserted into the Gt(ROSA)26Sor locus. This strain serves as a reporter strain, with successful Cre excision being indicated by EGFP expression in cre-expressing tissues. The expression level in this reporter strain is suitable for applications involving FACS but is too low for histological applications.
型号:GM-J#003967 -Cryorecovery
应用:These transgenic mice express Cre recombinase under the direction of a Rbp3 promoter. Homozygous mice are prone to eye defects and females may be infertile. Recombinase activity is detected in photoreceptor cells.
型号:GM-J#003966 -Available
应用:Specific cre expression in neuronal cells of these mice is controlled by the rat Synapsin I promoter. These mice may be useful when mated to floxed genes of interest in studies of neural development and disorders such as Neurofibromatosis type 1.
型号:GM-J#003960 -Cryorecovery
应用:These 98030B Prion.GFPCre mice express a transgene containing cre and green fluorescent protein with cre expression observed in the germline.
型号:GM-J#003920 -Cryorecovery
应用:Expression of lacZ in these mice is under the control of the CMV enhancer/chicken actin promoter and is widespread except in liver and lung tissue. When crossed with a Cre recombinase-expressing strain, lacZ expression is replaced with GFP in tissues expressing cre.
型号:GM-J#003919 -Cryorecovery
应用:These Z/AP reporter mice express a transgene containing a floxed Beta-geo and the human placental alkaline phosphatase gene with widespread expression of lacZ except in erythrocytes, chondrocytes and adipocytes.