型号:GM-J#003574 -Available Now
应用:Alb-cre mice are useful for deletion of loxP-flanked genes in the liver. Please note: this strain also is available on the 129 background (Stock No. 035593).
型号:GM-J#003573 -Available
应用:The RIP-Cre transgene has a 668 bp fragment of the rat insulin II promoter, nuclear-localized Cre recombinase, and a 2.1 kbp fragment from the human growth hormone gene. These RIP-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in pancreatic beta cells.
型号:GM-J#003556 -Available
应用:The Cre recombinase is under the control of the Mx1 promoter, which can be induced to high levels of transcription by administration of interferon alpha, interferon beta, or synthetic double-stranded RNA (such as poly I:C); enabling the "knockout" at any time during development in progeny of a floxed mutant mated to this transgenic.
型号:GM-J#003554 -Cryorecovery
应用:Col2a1-Cre (Col2-Cre) transgenic mice express Cre recombinase in a chondrocyte-specific pattern under the control of a Col2a1 promoter, which is active in differentiating chondrocytes, notochord and submandibular glands.
型号:GM-J#003553 -Cryorecovery
应用:These MMTV-Cre/Line D mice express a transgene containing the MMTV LTR promoter directing expression of Cre recombinase. High levels of recombination have been detected in the virgin and lactating mammary gland, salivary gland, seminal vesicle, skin, erythrocytes, B cells and T cells. MMTV-Cre Line D is not reported to have any significant expression in oocytes.
型号:GM-J#003552 -Cryorecovery
应用:These WAP-Cre mice express a transgene containing Cre recombinase with expression directed to secretory epithelium by the Wap promoter.
型号:GM-J#003551 -Cryorecovery
应用:These MMTV-Cre/Line A mice express a transgene containing the MMTV LTR promoter directing expression of Cre recombinase. High levels of recombination have been detected in the virgin and lactating mammary gland, salivary gland, seminal vesicle, skin, and various cells of the immune system. MMTV-Cre Line A also expresses cre in the female germline.
型号:GM-J#003504 -Cryorecovery
应用:The β-galactosidase-neomycin phosphotransferase fusion gene (βgeo)-trapped reverse orientation splice acceptor βgeo line 26 (ROSA26) locus was modified by gene targeting such that βgeo is expressed only after Cre-mediated excision of loxP-flanked DNA sequences. These mice may prove useful in the study of cell fate and cell migration during embryogenesis through recombinase-activated tagging.
型号:GM-J#003474 -Available
应用:These Gt(ROSA)26Sortm1Sor targeted mutant mice carry a loxP flanked neo cassette upstream of a β-galactosidase (lacZ) sequence. Removal of the neo cassette by cre recombination results in lacZ expression in cre-expressing tissues of the offspring. These mutant mice may be used as a Cre-reporter strain to test the tissue/cellular expression pattern of cre expressing mice.
型号:GM-J#003466 -Cryorecovery
应用:These Sycp1-Cre mice express a transgene containing cre under the transcriptional control of a region of the Sycp1 promoter activated at the leptotene-zygotene stage of the male meiosis.