型号：GM-J#004986 -Cryorecovery

应用：These NOD.RIPCre3 mice express cre recombinase in pancreatic beta cells.

型号：GM-J#004936 -Available

应用：Homozygotes exhibit disorganized ultrastructural wound matrix remodeling and defective macrophage infiltration and accumulation at sites of injury and infection. Mutant macrophage response to mycobacteria infection and pulmonary granulomatous response and inflammation are impaired. This mutant mouse strain may be useful in studies of carcinogenesis, tissue remodeling, wound repair, fibrosis and granulomatous diseases.

型号：GM-J#004847 -Cryorecovery

应用：These R26CreER mutant mice have a tamoxifen-inducible Cre-mediated recombination system driven by the endogenous mouse Gt(ROSA)26Sor promoter. When crossed with a strain containing a loxP site-flanked sequence of interest, this mutant is useful for generating tamoxifen-induced, Cre-mediated targeted deletions.

型号：GM-J#004783 -Cryorecovery

应用：These Sox2Cre transgenic mice express Cre recombinase under the control of the mouse Sox2 (SRY-box containing gene 2) promoter, and may be useful for generating epiblast-derived specific conditional mutations.

型号：GM-J#004782 -Cryorecovery

应用：A congenic version of this strain is available as Stock No. 018964.

型号：GM-J#004781 -Available Now

应用：The LysMcre knock-in/knock-out allele has a nuclear-localized Cre recombinase inserted into the first coding ATG of the lysozyme 2 gene (Lyz2); both abolishing endogenous Lyz2 gene function and placing NLS-Cre expression under the control of the endogenous Lyz2 promoter/enhancer elements. These LysMcre mice may be useful for Cre-lox studies of the myeloid cell lineage (monocytes, mature macrophages and granulocytes) and the innate immune response.

型号：GM-J#004746 -Cryorecovery

应用：A C57BL/6 congenic version of this strain is available as Stock No. 017491.

型号：GM-J#004744 -Cryorecovery

应用：This Esr1 mutant strain is a functional knock out of ERα. Female mice homozygous for this mutation are infertile, exhibit cystic ovaries that lack corpora lutea and hypoplastic uteri that are unresponsive to estrogen. Homozygous males show reduced testis weight associated with diminished sperm count. These mice may be suitable for use in studies related to estrogen signaling, estrous cycle, obesity, metabolic syndrome and hormonal regulation of a variety of organ systems.

型号：GM-J#004692 -Cryorecovery

应用：These HoxB7/Cre mice express a transgene containing Cre recombinase and show Low levels of expression in the dorsal root ganglia and the spinal cord.

型号：GM-J#004682 -Available Now

应用：When these CAGGCre-ERTM mice are bred with mice carrying a floxed target gene, tamoxifen-inducible Cre-mediated recombination results in deletion of the floxed sequences in widespread cells or tissues of the offspring, including developing embryos and cultured cells derived from transgenic mice.