产品型号：GM-J#004744 -Cryorecovery

产品应用：This Esr1 mutant strain is a functional knock out of ERα. Female mice homozygous for this mutation are infertile, exhibit cystic ovaries that lack corpora lutea and hypoplastic uteri that are unresponsive to estrogen. Homozygous males show reduced testis weight associated with diminished sperm count. These mice may be suitable for use in studies related to estrogen signaling, estrous cycle, obesity, metabolic syndrome and hormonal regulation of a variety of organ systems.